Postgraduate Resident, Department of Psychiatry, L N Medical College and J K Hospital, Bhopal, Madhya Pradesh, India, Corresponding Author.
Professor, Department of Medicine, Department of Psychiatry, L N Medical College and J K Hospital, Bhopal, Madhya Pradesh, India.
J Assoc Physicians India. 2024 Sep;72(9):e10-e13. doi: 10.59556/japi.72.0647.
Erectile dysfunction (ED) is a well-studied entity in diabetes mellitus (DM). As with DM, prediabetes also appears to be associated with changes in microvascular-related comorbidities. These include retinopathy, neuropathy, nephropathy, and ED. ED is a condition characterized by an inability to maintain penile erection for adequate sexual activity, either consistently or recurrently. Endothelial damage due to any cause corresponding to hyperglycemia signifies the relationship between prediabetes and ED. While the evaluation of ED in diabetics has been extensively studied worldwide, there is a paucity of knowledge about ED among prediabetics.
The study type was observational and was conducted at a tertiary center in India. Adult males aged 18-50 years with prediabetes were included in the study over a duration of 18 months. Evaluation for ED was performed using the International Index of Erectile Function 5 (IIEF-5).
A total of 139 participants were enrolled in the present study. The severity of ED was categorized as follows: 32.4% of participants had mild ED, 11.5% had mild-to-moderate ED, and 6.5% had moderate ED. A positive association was found between prediabetes-related parameters and ED.
There is a significant prevalence of ED in prediabetic males compared to the general population, as found in our study. Overall, 50.3% of participants were found to have ED. We recommend exploring this subject with more structured and larger studies.
勃起功能障碍(ED)是糖尿病(DM)中研究得很好的一种病症。与 DM 一样,糖尿病前期似乎也与微血管相关合并症的变化有关。这些合并症包括视网膜病变、神经病变、肾病和 ED。ED 是一种以阴茎无法维持足够的勃起以进行充分的性行为为特征的病症,无论是持续的还是反复的。由于高血糖对应的任何原因导致的内皮损伤表明了糖尿病前期和 ED 之间的关系。虽然全球范围内对糖尿病患者 ED 的评估已经进行了广泛研究,但对于糖尿病前期患者的 ED 知之甚少。
本研究类型为观察性研究,在印度的一家三级中心进行。在 18 个月的时间里,纳入了年龄在 18-50 岁之间患有糖尿病前期的成年男性。使用国际勃起功能指数 5(IIEF-5)对 ED 进行评估。
本研究共纳入 139 名参与者。ED 的严重程度分类如下:32.4%的参与者有轻度 ED,11.5%有轻度至中度 ED,6.5%有中度 ED。发现糖尿病前期相关参数与 ED 之间存在正相关。
与一般人群相比,我们的研究发现,糖尿病前期男性中 ED 的患病率显著更高。总的来说,50.3%的参与者有 ED。我们建议通过更多结构化和更大规模的研究来探讨这个问题。