Department of Pathology and Lab Medicine, All India Institute of Medical Sciences, Bibinagar, Telangana, India.
Department of Pathology/Lab Medicine, All India Institute of Medical Sciences, Mangalagiri, Andhra Pradesh, India.
Diagn Cytopathol. 2024 Dec;52(12):779-788. doi: 10.1002/dc.25404. Epub 2024 Sep 19.
The cytology features of neoplastic paratesticular lesions are mostly documented as case reports. Thus, we conducted a case report-based literature review to identify the characteristics of paratesticular neoplasms and tried to determine the significance of FNAC in these tumors.
The studies were searched using PubMed and Scopus. The quality assessment was done using the JBI critical appraisal checklist for case reports. The articles that received an overall rating of "Include" underwent data extraction. The data were extracted from the articles and analyzed.
We included 34 case reports from 33 published articles. The mean age of patients was 44.74 (13-85) years, and the most common clinical manifestation was scrotal swelling (70.59%, 24/34). Lesions were commonly observed on the right side (65.63%, 21/32), and the most common tumor site was epididymis (35.29%, 12/34). A total of 38.24% (13/34) cases were nonmalignant, and 61.76% (21/34) were malignant on the cytological diagnosis. The adenomatoid tumor (53.85, 7/13) was the most common nonmalignant tumor. Other entities were schwannoma, benign spindle cell neoplasm with atypia, nerve sheath tumor, lipoma, undifferentiated pleomorphic sarcoma, rhabdomyosarcoma, epithelioid sarcoma, liposarcoma, malignant rhabdoid tumor, pigmented neuroectodermal tumor of infancy and mesothelioma. Considering the malignant and nonmalignant groups, the sensitivity, specificity, and diagnostic accuracy of cytology were 95.00%, 84.62%, and 90.91%, respectively.
Cytopathologists should be familiar with the cytological features of various malignant and nonmalignant paratesticular tumors to prevent unnecessarily invasive surgical management. The current systematic review emphasizes usefulness of FNAC in the preoperative cytological identification of paratesticular tumors.
肿瘤性副睾周围病变的细胞学特征主要以病例报告的形式记录。因此，我们进行了一项基于病例报告的文献复习，以确定副睾周围肿瘤的特征，并试图确定细针抽吸细胞学检查在这些肿瘤中的意义。
使用 PubMed 和 Scopus 进行研究检索。使用 JBI 病例报告评估清单进行质量评估。总体评价为“包括”的文章进行了数据提取。从文章中提取数据并进行分析。
我们纳入了来自 33 篇已发表文章的 34 例病例报告。患者的平均年龄为 44.74 岁（13-85 岁），最常见的临床表现为阴囊肿胀（70.59%，24/34）。病变常见于右侧（65.63%，21/32），最常见的肿瘤部位是附睾（35.29%，12/34）。细胞学诊断的非恶性病变占 38.24%（13/34），恶性病变占 61.76%（21/34）。良性肿瘤中最常见的是腺瘤样肿瘤（53.85%，7/13）。其他实体瘤有神经鞘瘤、良性梭形细胞肿瘤伴非典型性、神经鞘瘤、脂肪瘤、未分化多形性肉瘤、横纹肌肉瘤、上皮样肉瘤、脂肪肉瘤、恶性横纹肌样瘤、婴儿色素性神经外胚层肿瘤和间皮瘤。考虑到恶性和非恶性组，细胞学的敏感性、特异性和诊断准确性分别为 95.00%、84.62%和 90.91%。
细胞病理学家应熟悉各种恶性和非恶性副睾周围肿瘤的细胞学特征，以避免不必要的侵袭性手术治疗。本系统评价强调了细针抽吸细胞学检查在术前识别副睾周围肿瘤中的有用性。
