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孤立性心脏结节病:临床挑战。

Isolated cardiac sarcoidosis: A clinical challenge.

机构信息

Departments of Cardiology and Medicine, Wexham Park Hospital, Frimley Health NHS Foundation Trust, United Kingdom.

Departments of Cardiology and Medicine, Wexham Park Hospital, Frimley Health NHS Foundation Trust, United Kingdom.

出版信息

Clin Med (Lond). 2024 Nov;24(6):100245. doi: 10.1016/j.clinme.2024.100245. Epub 2024 Sep 19.

Abstract

Sarcoidosis is an inflammatory disease characterised by non-caseating granulomas of unclear aetiology. Isolated cardiac sarcoidosis (ICS) is rare and occurs when there is granulomatous infiltration of myocardial tissue without evidence of extracardiac sarcoidosis. The heterogeneity in clinical manifestations often presents a diagnostic challenge which leads to delays in treatment initiation. Our case highlights the often quiescent presentation of ICS, the importance of early treatment and the diagnostic challenges that contribute to its underdiagnosis.

摘要

结节病是一种以非干酪样肉芽肿为特征的炎症性疾病,病因不明。孤立性心脏结节病(ICS)较为罕见,是指心肌组织有肉芽肿浸润而无心脏外结节病的证据。临床表现的异质性常常带来诊断挑战,导致治疗开始延迟。本病例突出了 ICS 常呈惰性表现,强调了早期治疗的重要性以及导致其漏诊的诊断挑战。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/67c2/11466626/43f2e062e37d/gr1.jpg

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