Department of Pulmonary and Critical Care Medicine, Jinhua Municipal Central Hospital, Jinhua, Zhejiang, China.
Department of Pulmonary and Critical Care Medicine, Jinhua Municipal Central Hospital, No. 365, East Renmin Road, Jinhua, Zhejiang 321000, China.
Ther Adv Respir Dis. 2024 Jan-Dec;18:17534666241281669. doi: 10.1177/17534666241281669.
Tranexamic acid (TA) is a well-established antifibrinolytic agent utilized across various medical scenarios to manage bleeding, including surgical, traumatic, postpartum, and upper gastrointestinal bleeding. Despite its widespread application, the systematic evaluation of TA's efficacy in achieving hemostasis during interventional pulmonary procedures remains limited. This review aims to address this gap by examining the utility and effectiveness of TA in promoting hemostasis during pulmonary interventions, encompassing procedures such as bronchial artery embolization, percutaneous lung biopsy, bronchoscopy, and pleural procedures. By synthesizing existing evidence, this review seeks to provide valuable insights into the potential role of TA in mitigating hemorrhage following interventional pulmonary procedures, thereby informing clinical practice and guiding future research endeavors.
氨甲环酸（TA）是一种已被广泛认可的抗纤维蛋白溶解剂，在多种医疗场景中被用于控制出血，包括手术、创伤、产后和上消化道出血。尽管 TA 被广泛应用，但系统评估其在介入性肺程序中实现止血效果的研究仍有限。本综述旨在通过研究 TA 在支气管动脉栓塞、经皮肺活检、支气管镜检查和胸膜程序等肺介入过程中促进止血的效用和有效性来填补这一空白。通过综合现有证据，本综述旨在为 TA 在减轻介入性肺程序后出血方面的潜在作用提供有价值的见解，从而为临床实践提供信息并指导未来的研究工作。
