原核 Argonaute 蛋白招募解旋酶-核酸酶来降解入侵的质粒。
A prokaryotic Argonaute protein recruits a helicase-nuclease to degrade invading plasmids.
机构信息
Max Planck Unit for the Science of Pathogens, 10117 Berlin, Germany.
Max Planck Unit for the Science of Pathogens, 10117 Berlin, Germany; Institute for Biology, Humboldt University Berlin, 10115 Berlin, Germany.
出版信息
Cell. 2024 Sep 19;187(19):5223-5225. doi: 10.1016/j.cell.2024.08.031.
PMID:39303689
Abstract
DdmDE is a novel plasmid defense system that was discovered in the seventh pandemic Vibrio cholerae strain of the biotype O1 EI Tor. In this issue of Cell, Yang and coworkers reveal the mechanisms underlying the assembly and activation of the DdmDE defense system.
摘要
DdmDE 是一种新型质粒防御系统，最初在第七次大流行的生物型 O1 EI Tor 霍乱弧菌菌株中被发现。在本期《Cell》杂志中，Yang 及其同事揭示了 DdmDE 防御系统组装和激活的机制。
Zotero 插件