Catty J P, Hole N J, Catty D
Mol Immunol. 1985 Aug;22(8):949-53. doi: 10.1016/0161-5890(85)90081-1.
Using an antiserum raised in b(bas)/b(bas)-suppressed rabbits to kappa 2 light chain we have shown that the kappa 2 light chain is an isotype of kappa 1, present in the majority of, if not all, rabbits. It probably exists in at least 2 allelic forms. It is capable of producing a functional antibody molecule (auto anti-b6) and compensates for the absence of kappa 1 light chain in homozygous b6-suppressed rabbits.
我们使用在b(bas)/b(bas)抑制的兔子中产生的针对kappa 2轻链的抗血清,证明了kappa 2轻链是kappa 1的一种同种型,存在于大多数(如果不是全部)兔子中。它可能至少以2种等位基因形式存在。它能够产生功能性抗体分子(自身抗b6),并补偿纯合b6抑制兔子中kappa 1轻链的缺失。