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急性心房梗死:临床实践中一个相对被忽视且认识不足的实体。

Acute atrial infarction: a relatively neglected and under-recognized entity in clinical practice.

作者信息

Di Chengye, Wang Haijiang, Wang Mingming, Wang Qun, Wu Yanxi, Li Longyu, Zhang Yan, Lin Wenhua

机构信息

Cardiac Electrophysiology Unit, First Department of Cardiology, TEDA International Cardiovascular Hospital, 3rd Street, Tianjin Economic-Technological Development Area, 300457, Tianjin, China.

College of Clinical Cardiology, Tianjin Medical University, Tianjin, China.

出版信息

Herz. 2025 Apr;50(2):122-134. doi: 10.1007/s00059-024-05272-z. Epub 2024 Sep 24.

DOI:10.1007/s00059-024-05272-z
PMID:39316092
Abstract

BACKGROUND

Electrocardiograms (ECGs) and angiographic features indicative of acute atrial infarction (AAI) often go unnoticed and are under-recognized in clinical practice.

METHODS

In this retrospective observational study, we analyzed the data of 3981 out of 9803 patients (40.61%) who were referred to our hospital for angiography and/or percutaneous coronary intervention due to acute coronary syndrome (ACS). These patients were diagnosed with acute ST segment elevation myocardial infarction (AMI) affecting the inferior, posterior, and/or right ventricular regions.

RESULTS

Of the 3981 patients, 270 (6.78%) had involvement of the main coronary atrial branch meeting the angiographic criteria for AAI. Among the 270 patients identified, the right coronary artery was diagnosed as the infarct-related artery (IRA) in 187 patients (group R), while the left circumflex artery was the IRA in 83 patients (group L). The incidence of PR-segment deviation was similar between the two groups (65.2% in group R vs. 66.3% in group L, p = 0.870), as was occurrence of atrial tachyarrhythmia (67.4% vs. 55.4%, p = 0.059). The prevalence of P wave morphology abnormalities (29.9% vs. 49.4%, p = 0.005) and sinus bradycardia or arrest (25.1% vs. 66.3%, p < 0.001) was significantly lower in Group R than in Group L.

CONCLUSION

Acute atrial infarction represents a distinct yet frequently overlooked clinical entity. Clinicians should consider the potential for atrial arrhythmias, thromboembolism, hemodynamic instability, and atrial rupture when diagnosing AAI.

摘要

背景

提示急性心房梗死(AAI)的心电图(ECG)和血管造影特征在临床实践中常被忽视且未得到充分认识。

方法

在这项回顾性观察研究中,我们分析了9803例因急性冠状动脉综合征(ACS)转诊至我院进行血管造影和/或经皮冠状动脉介入治疗的患者中的3981例(40.61%)的数据。这些患者被诊断为影响下壁、后壁和/或右心室区域的急性ST段抬高型心肌梗死(AMI)。

结果

在3981例患者中,270例(6.78%)主冠状动脉心房支受累,符合AAI的血管造影标准。在确诊的270例患者中,右冠状动脉被诊断为梗死相关动脉(IRA)的有187例(R组),而左旋支动脉为IRA的有83例(L组)。两组PR段偏移的发生率相似(R组为65.2%,L组为66.3%,p = 0.870),房性快速心律失常的发生率也相似(67.4%对55.4%,p = 0.059)。R组P波形态异常(29.9%对49.4%,p = 0.005)和窦性心动过缓或停搏(25.1%对66.3%,p < 0.001)的发生率显著低于L组。

结论

急性心房梗死是一种独特但常被忽视的临床实体。临床医生在诊断AAI时应考虑房性心律失常、血栓栓塞、血流动力学不稳定和心房破裂的可能性。

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