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鞘内泵巴氯芬取出后选择性脊神经后根切断术:单中心经验及文献复习。

Selective dorsal rhizotomy after baclofen intrathecal pump removal: a single-center experience and review of the literature.

机构信息

Functional Neurosurgery Unit, Unit of Neurosurgery, Department of Neurosciences, Santobono-Pausilipon Children's Hospital, Naples, Italy.

Unit of Neurosurgery, Department of Biomedicine, Neuroscience and Advanced Diagnostics, Post Graduate Residency Program in Neurosurgery, University of Palermo, Palermo, Italy.

出版信息

Childs Nerv Syst. 2024 Dec;40(12):4089-4094. doi: 10.1007/s00381-024-06618-y. Epub 2024 Sep 24.

Abstract

PURPOSE

Selective dorsal rhizotomy (SDR) and intrathecal baclofen (ITB) pump placement are two surgical options in children affected by spasticity secondary to cerebral palsy . The latest literature is an enlarging indication for SDR in case of ITB failure in non-ambulant patients as an alternative to pump reimplantation to reduce spasticity and facilitate patients' care.

METHODS

A retrospective single-center study has screened all children diagnosed with spastic tetraparesis who underwent in the last 10 years SDR and had previously ITB pump implanted. A cohort of six patients was pooled out. Furthermore, pertinent literature has been reviewed.

RESULTS

Indication for pump removal was pump pocket infection, parents' decision, and poor response to ITB. Patients' amount of lifetime with the pump implanted has been 6.9 years. The preoperative and postoperative Ashworth scores were statistically different in both procedures (p = 0.005 and p = 0.,02).

CONCLUSIONS

Only two studies investigated the pediatric population undergoing SDR in the occurrence of ITB pump removal. Authors are offering SDR to all children, regardless of GMFCS groups and previous ITB pump placement. In conclusion, SDR represents a valid tool in neurosurgeon's hands to help ameliorate patients' long-lasting quality of life, reducing the severity of the spasticity and leading to better management by caregivers.

摘要

目的

选择性脊神经后根切断术(SDR)和鞘内巴氯芬(ITB)泵植入是两种针对脑瘫引起的痉挛的手术选择。最新的文献表明,对于非卧床患者的 ITB 泵失败,SDR 是一种扩大的适应证,可替代重新植入泵以减轻痉挛并方便患者护理。

方法

回顾性单中心研究筛选了过去 10 年中所有接受 SDR 治疗且先前已植入 ITB 泵的痉挛性四肢瘫儿童。汇集了 6 名患者。此外,还回顾了相关文献。

结果

泵移除的指征是泵袋感染、家长决定和对 ITB 的反应不佳。患者一生中植入泵的时间为 6.9 年。两种手术的术前和术后 Ashworth 评分均有统计学差异(p=0.005 和 p=0.02)。

结论

只有两项研究调查了在 ITB 泵移除的情况下接受 SDR 的儿科人群。作者为所有儿童提供 SDR,无论 GMFCS 组和先前的 ITB 泵放置如何。总之,SDR 是神经外科医生手中的有效工具,可以帮助改善患者的长期生活质量,减轻痉挛的严重程度,并使护理人员更好地管理。

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