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与娱乐性使用一氧化二氮相关的冻伤:瑞典病例系列中的发病率、管理及并发症

Frostbite injuries related to recreational nitrous oxide use: incidence, management, and complications in a Swedish case series.

作者信息

Liu Yihang, Svennersten Karl, Schwartz David, Huss Fredrik, Falk-Delgado Alberto

机构信息

Department of Molecular Medicine and Surgery, Karolinska Institutet, Stockholm, Sweden.

Department of Acute and Trauma Surgery, Karolinska University Hospital, Stockholm, Sweden.

出版信息

JPRAS Open. 2024 Aug 5;42:162-169. doi: 10.1016/j.jpra.2024.07.019. eCollection 2024 Dec.

Abstract

BACKGROUND

Nitrous oxide (NO) use in recreational settings has been increasing in Sweden and Europe and consequently, the related injuries are also increasing. We aimed to investigate the incidence, management, and surgical outcomes of frostbite injury (FI) related to NO use.

MATERIAL AND METHOD

All patients in a 22-month period from 2021 to 2022 presenting with FI related to NO abuse from 2 plastic surgery clinics (1 national burn center) were identified. Data regarding patient comorbidity, mechanism of injury, initial management, treatment, and follow-up were investigated. Complications following surgery were categorized into minor (treated in outpatient setting) and major (requiring reoperation) complications.

RESULTS

In total, 9 patients were identified; among them, 5 patients provided consent and were included in the study. Direct contact with the gas canister was the most common injury mechanism (n = 4). All but 1 patient contracted full-thickness injuries, and these 4 patients later required surgery. The medial thigh was the most common area of injury. Outpatient clinic visits were common (mean 4.8 visits/patient). Surgical complications were common and all operated patients were diagnosed with minor complications and half of them with major complications (wound dehiscence and scar contracture).

CONCLUSION

Frostbite injuries arising from recreational NO use are complex and often require surgical intervention that may lead to complications. With the increasing incidence of NO abuse in Sweden, further research is crucial to address this emerging public health concerns and optimize treatment strategies for these distinctive injuries.

摘要

背景

在瑞典和欧洲,氧化亚氮(NO)在娱乐场合的使用呈上升趋势,因此,与之相关的伤害也在增加。我们旨在调查与使用NO相关的冻伤(FI)的发生率、处理方法及手术效果。

材料与方法

确定了2021年至2022年22个月期间来自2家整形外科诊所(1家国家烧伤中心)的所有因滥用NO而出现FI的患者。调查了患者的合并症、损伤机制、初始处理、治疗及随访情况。术后并发症分为轻微并发症(在门诊处理)和严重并发症(需要再次手术)。

结果

共确定9例患者;其中5例患者同意并纳入研究。与气瓶直接接触是最常见的损伤机制(n = 4)。除1例患者外,其余均为全层损伤,这4例患者后来需要手术治疗。大腿内侧是最常见的损伤部位。门诊就诊很常见(平均每位患者4.8次就诊)。手术并发症很常见,所有接受手术的患者均被诊断为有轻微并发症,其中一半有严重并发症(伤口裂开和瘢痕挛缩)。

结论

娱乐性使用NO引起的冻伤很复杂,通常需要手术干预,而这可能会导致并发症。随着瑞典NO滥用发生率的上升,进一步研究对于解决这一新兴的公共卫生问题以及优化针对这些特殊损伤的治疗策略至关重要。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/80b6/11424756/8bdc5a7fae35/gr1.jpg

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