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镰状细胞病患儿疼痛发作的住院治疗管理:综述

Inpatient Management of Pain Episodes in Children with Sickle Cell Disease: A Review.

作者信息

Barnawi Zhour, Thomas Ronay, Peddinti Radhika, Abou Baker Nabil

机构信息

Department of Pediatrics, Section of Hematology-Oncology and Bone Marrow Transplant, University of Chicago Medicine, Chicago, IL 60637, USA.

Department of Pediatrics, King Abdulaziz University, Jeddah 21589, Saudi Arabia.

出版信息

Children (Basel). 2024 Sep 10;11(9):1106. doi: 10.3390/children11091106.

DOI:10.3390/children11091106
PMID:39334638
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11430294/
Abstract

Sickle cell disease (SCD) is the most common hemoglobinopathy in the world. Sickle cell vaso-occlusive episodes (VOEs) are very painful acute events and the most common complication as well as reason for hospitalization. SCD pain is best evaluated holistically with a pain functional assessment to aid in focusing pain management on reducing pain in addition to improving function. Patients with SCD have long endured structural racism and negative implicit bias surrounding the management of pain. Thus, it is important to approach the management of inpatient pain systematically with the use of multi-modal medications and nonpharmacologic treatments. Furthermore, equitable pain management care can be better achieved with standardized pain plans for an entire system and individualized pain plans for patients who fall outside the scope of the standardized pain plans. In this article, we discuss the best practices to manage SCD VOEs during an inpatient hospitalization.

摘要

镰状细胞病(SCD)是世界上最常见的血红蛋白病。镰状细胞血管闭塞性发作(VOEs)是非常痛苦的急性事件,也是最常见的并发症以及住院原因。SCD疼痛最好通过疼痛功能评估进行全面评估,以帮助将疼痛管理重点放在减轻疼痛以及改善功能上。SCD患者长期遭受围绕疼痛管理的结构性种族主义和负面隐性偏见。因此,使用多模式药物和非药物治疗系统地处理住院患者的疼痛很重要。此外,通过整个系统的标准化疼痛计划以及针对超出标准化疼痛计划范围的患者的个性化疼痛计划,可以更好地实现公平的疼痛管理护理。在本文中,我们讨论了住院期间管理SCD VOEs的最佳实践。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5031/11430294/91af624c4e59/children-11-01106-g005.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5031/11430294/c6c5890e9367/children-11-01106-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5031/11430294/77c74946a2d2/children-11-01106-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5031/11430294/a9067bc9baf6/children-11-01106-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5031/11430294/ac928d166fdc/children-11-01106-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5031/11430294/91af624c4e59/children-11-01106-g005.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5031/11430294/c6c5890e9367/children-11-01106-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5031/11430294/77c74946a2d2/children-11-01106-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5031/11430294/a9067bc9baf6/children-11-01106-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5031/11430294/ac928d166fdc/children-11-01106-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5031/11430294/91af624c4e59/children-11-01106-g005.jpg

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本文引用的文献

1
Impact of hospitalized vaso-occlusive crises in the previous calendar year on mortality and complications in adults with sickle cell disease: a French population-based study.前一个日历年住院血管闭塞性危象对镰状细胞病成人患者死亡率和并发症的影响:一项基于法国人群的研究。
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镰状细胞病的疾病修正疗法概述。
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A cognitive-behavioral digital health intervention for sickle cell disease pain in adolescents: a randomized, controlled, multicenter trial.一项针对青少年镰状细胞病疼痛的认知行为数字健康干预的随机、对照、多中心试验。
Pain. 2024 Jan 1;165(1):164-176. doi: 10.1097/j.pain.0000000000003009. Epub 2023 Sep 21.
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Treating Chronic Pain in Sickle Cell Disease - The Need for a Biopsychosocial Model.镰状细胞病慢性疼痛的治疗——生物心理社会模型的必要性
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Characterisation of medical conditions of children with sickle cell disease in the USA: findings from the 2007-2018 National Health Interview Survey (NHIS).美国镰状细胞病儿童的医学状况特征:2007-2018 年全国健康访谈调查(NHIS)的结果。
BMJ Open. 2023 Feb 28;13(2):e069075. doi: 10.1136/bmjopen-2022-069075.
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Intranasal fentanyl and discharge from the emergency department among children with sickle cell disease and vaso-occlusive pain: A multicenter pediatric emergency medicine perspective.鼻内芬太尼与镰状细胞病伴血管阻塞性疼痛患儿从急诊科出院:多中心儿科急诊医学视角。
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