Spachmann Philipp J, Radlmaier Maximilian, Denzinger Stefan, Burger Maximilian, Breyer Johannes, Otto Wolfgang, Schnabel Marco J, Vergho Daniel
Department of Urology, Caritas St. Josef Medical Center Regensburg, University of Regensburg, 93053 Regensburg, Germany.
Urologie Landau and Urologie Plattling, 94405 Landau/Isar, Germany.
Antibiotics (Basel). 2024 Sep 16;13(9):890. doi: 10.3390/antibiotics13090890.
Recurrent cystitis in women represents an everyday challenge; however, little to no data regarding this population are available. This study aimed to evaluate this collective with respect to a rational calculated antibiotic therapy. Urine cultures and antibiograms from a urological office were retrospectively evaluated from patient data collected between January 2017 and June 2019. The evaluation was conducted using SPSS ©. In total, 84 female patients, who were aged between 18 and 87 years old (median 60 years), suffered from recurrent cystitis. was found in 53.9% of cases, and enterococci were each found in 6.7%, and spp. and were each found in 5.6%. The resistance levels to ciprofloxacin (CIP), trimethoprim-sulfamethoxazole (TRS), nitrofurantoin (NIT), and nitroxoline (NOX) were 18.2%, 30.7%, 16.1%, and 12.5% in the tested cases, respectively. Regarding , resistance to CIP, TRS, and NIT was found in 17.8%, 25%, and 4.2% of the tested cases, and no resistance to NOX was found. The resistance level to CIP was in a tolerable range of <20% in the overall cohort and the subgroup. More than a quarter of the bacteria were resistant to TRS. The low resistance rates for NIT and NOX are remarkable, promoting the use of these substances if they are not yet used.
女性复发性膀胱炎是一项日常挑战;然而,关于这一人群的数据很少甚至没有。本研究旨在评估针对合理计算的抗生素治疗的这一群体。对2017年1月至2019年6月期间收集的患者数据进行回顾性评估,这些数据来自一家泌尿外科诊所的尿培养和药敏试验结果。使用SPSS©进行评估。共有84名年龄在18至87岁(中位数60岁)的女性患者患有复发性膀胱炎。在53.9%的病例中发现了[具体细菌名称未给出],肠球菌各占6.7%,[其他细菌名称未给出]菌属和[其他细菌名称未给出]各占5.6%。在测试病例中,对环丙沙星(CIP)、甲氧苄啶-磺胺甲恶唑(TRS)、呋喃妥因(NIT)和硝羟喹啉(NOX)的耐药率分别为18.2%、30.7%、16.1%和12.5%。对于[具体细菌名称未给出],在测试病例中对CIP、TRS和NIT的耐药率分别为17.8%、25%和4.2%,未发现对NOX的耐药情况。在整个队列和[具体亚组未给出]亚组中,对CIP的耐药率处于<20%的可接受范围内。超过四分之一 的细菌对TRS耐药。NIT和NOX的低耐药率值得注意,如果尚未使用这些药物,可推广使用。