Dasgupta Tisha, Boulding Harriet, Easter Abigail, Sutedja Tania, Khalil Asma, Mistry Hiten D, Horgan Gillian, Van Citters Aricca D, Nelson Eugene C, von Dadelszen Peter, Duncan Emma L, Silverio Sergio A, Magee Laura A
Department of Women & Children's Health, School of Life Course & Population Sciences, King's College London, London SE1 1UL, UK.
The Policy Institute, Faculty of Social Science & Public Policy, King's College London, London WC2B 6LE, UK.
Vaccines (Basel). 2024 Sep 11;12(9):1042. doi: 10.3390/vaccines12091042.
Maternal vaccination during pregnancy, in general and against COVID-19 infection, offers protection to both mother and baby, but uptake remains suboptimal. This study aimed to explore the perceptions regarding COVID-19 vaccination in pregnancy, particularly for marginalised populations and those living with social or medical complexity. A total of 96 semi-structured in-depth interviews were conducted with 40 women, 15 partners, 21 HCPs, and 20 policy makers, across all four nations of the United Kingdom (UK), discussing their lived experience of utilising, delivering, or developing policy for COVID-19 vaccination in pregnancy during the pandemic. Three themes were derived: (1) historical and social context, (2) communication of information and guidance, and (3) appraisal and action. Together these captured the participants' legacy of mistrust in drugs during pregnancy; prior positive experiences; concerns about missing information, conflicting information, or false information about COVID-19 vaccines; and confusing guidance for pregnant women. The final theme describes the participants' behaviour and actions undertaken consequent to their experiences and the available information. The findings suggest efforts to improve COVID-19 vaccination in pregnancy may be best focused on personalised communication of information. A trusting relationship and prior positive experiences with other vaccines, both in and outside of pregnancy, positively influenced perceptions of COVID-19 vaccination.
孕期接种疫苗,总体而言以及针对新冠病毒感染的接种,能为母亲和婴儿提供保护,但接种率仍不尽人意。本研究旨在探讨对孕期接种新冠疫苗的看法,特别是针对边缘化人群以及那些面临社会或医疗复杂性的人群。在英国的四个国家,共对40名女性、15名伴侣、21名医护人员和20名政策制定者进行了96次半结构化深度访谈,讨论了他们在疫情期间在孕期使用、提供或制定新冠疫苗接种政策方面的实际经历。得出了三个主题:(1)历史和社会背景,(2)信息与指导的传达,(3)评估与行动。这些主题共同反映了参与者在孕期对药物不信任的遗留问题;先前的积极经历;对新冠疫苗信息缺失、信息冲突或虚假信息的担忧;以及针对孕妇的令人困惑的指导。最后一个主题描述了参与者基于自身经历和现有信息所采取的行为和行动。研究结果表明,改善孕期新冠疫苗接种的努力可能最好集中在个性化的信息传达上。在孕期内外与其他疫苗建立的信任关系和先前的积极经历,对新冠疫苗接种的看法产生了积极影响。