Van Nieuwenhuyse Brieuc, Balcaen Mathilde, Chatzis Olga, Haenecour Astrid, Derycke Emilien, Detaille Thierry, Clément de Cléty Stéphan, Boulanger Cécile, Belkhir Leïla, Yombi Jean-Cyr, De Greef Julien, Cornu Olivier, Docquier Pierre-Louis, Lentini Audrey, Menten Renaud, Rodriguez-Villalobos Hector, Verroken Alexia, Djebara Sarah, Merabishvili Maya, Griselain Johann, Pirnay Jean-Paul, Houtekie Laurent, Van der Linden Dimitri
Institute of Experimental and Clinical Research, Pediatric Department (IREC/PEDI), Université catholique de Louvain - UCLouvain, Brussels, Belgium.
Pediatric Intensive Care Unit, Cliniques universitaires Saint-Luc, Université catholique de Louvain - UCLouvain, Brussels, Belgium.
Front Cell Infect Microbiol. 2024 Sep 17;14:1354681. doi: 10.3389/fcimb.2024.1354681. eCollection 2024.
Maximal standard-of-care (SOC) management could not stop the life-threatening progression of a necrotizing fasciitis induced by Panton-Valentine Leukocidin-producing Methicillin-Resistant (MRSA) in a 12-year-old boy. Multi-route phage therapy was initiated along with antibiotics against and , eventually leading to full recovery with no reported adverse events.
对于一名12岁男孩,最大标准治疗(SOC)管理无法阻止由产生杀白细胞素的耐甲氧西林金黄色葡萄球菌(MRSA)引起的坏死性筋膜炎的危及生命的进展。在使用针对[具体病菌名称1]和[具体病菌名称2]的抗生素的同时开始了多途径噬菌体治疗,最终实现完全康复,且未报告不良事件。