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在非行走型神经肌肉性早发性脊柱侧弯患者中使用磁控生长棒进行脊柱至骨盆的“T形结构”:一项初步研究。

Spine to pelvis "T-Construct" using magnetic controlled growing rods in non-walkers neuromuscular early-onset scoliosis: a preliminary study.

作者信息

Thouement Clélia, Saghbini Elie, Eloy Gauthier, Pietton Raphaël, Vialle Raphaël, Langlais Tristan

机构信息

Department of Pediatric Orthopedics, Armand-Trousseau Hospital, Sorbonne University, Paris, France.

Department of Pediatric Orthopedics, Armand-Trousseau Hospital, Sorbonne University, Paris, France; The MAMUTH Hospital University Department for Innovative Therapies in Musculoskeletal Disease Sorbonne University, Paris, France.

出版信息

Orthop Traumatol Surg Res. 2025 May;111(3):104012. doi: 10.1016/j.otsr.2024.104012. Epub 2024 Oct 1.

Abstract

BACKGROUNDS

Magnetic controlled growing rods (MCGRs) have been proven to be effective in controlling early onset neuromuscular scoliosis but no study has evaluated the combination with a sacro-bi-iliac construct. The aim of our study is to report surgical management of early onset non-walkers neuromuscular scoliosis correction using MCGRs associated with a sacro-bi-iliac "T-construct" and its mid-term outcomes. Our hypothesis was that this set-up provided well correction of the pelvic obliquity and that this correction was maintained over time.

METHODS

A retrospective single-center study was conducted including all consecutive neuromuscular early onset scoliosis who underwent spinopelvic fixation using "T-construct" with two MCGRS. Four millimeters lengthening was performed every 4 months during outpatient clinics sessions. All children had a low-dose biplanar stereoradiography in EOS-Chair at pre/postoperative phase, each outpatient clinic appointment and last follow-up.

RESULTS

Eighteen patients were included and 17 analyzed at the last follow-up. The mean age at surgery was 9.5 (range from 5 to 12 years), the mean follow-up was 4,7 years (range from 2.5 to 6.6 years) and 8 patients had a Risser stage above four. The global complication rate was 35% (N = 6/17 patients) including three medical and three mechanical complications related to "T-construct", while the reoperation rate was 18% (N = 2 patients for wound debridement and one for iterative pelvic fixation). Cobb angle and pelvic obliquity were significantly improved by surgery (mean correction was 33.2 ° (55%) and 11 ° (77%) respectively; p < 0.001). At the last follow-up, we noted a loss of frontal Cobb angle correction (p < 0.01) whereas we did not observe any significant loss of pelvic obliquity (p > 0.9).

CONCLUSIONS

Although the global complication rate was 35% (half of which are mechanical complications), the treatment combining pelvic T-construct and MCGRs provides satisfactory correction of pelvic obliquity correction, good maintenance in the medium term and may be a procedure to consider for the surgical treatment of early onset neuromuscular scoliosis.

LEVEL OF EVIDENCE

IV; Retrospective cohort prognostic study.

摘要

背景

磁控生长棒(MCGRs)已被证明在控制早发性神经肌肉型脊柱侧弯方面有效,但尚无研究评估其与骶髂结构联合使用的效果。我们研究的目的是报告使用与骶髂“T形结构”相关的MCGRs对早发性不能行走的神经肌肉型脊柱侧弯进行矫正的手术治疗及其中期结果。我们的假设是,这种设置能很好地矫正骨盆倾斜,且这种矫正能随时间维持。

方法

进行了一项回顾性单中心研究,纳入所有连续接受使用两个MCGRs的“T形结构”进行脊柱骨盆固定的早发性神经肌肉型脊柱侧弯患者。在门诊期间,每4个月进行4毫米的延长。所有儿童在术前/术后阶段、每次门诊预约和最后一次随访时,均在EOS椅上进行低剂量双平面立体放射摄影。

结果

纳入18例患者,17例在最后一次随访时进行分析。手术时的平均年龄为9.5岁(范围为5至12岁),平均随访时间为4.7年(范围为2.5至6.6年),8例患者的Risser分期高于4期。总体并发症发生率为35%(n = 6/17例患者),包括3例与“T形结构”相关的医疗并发症和3例机械并发症,而再手术率为18%(2例患者因伤口清创,1例因反复骨盆固定)。手术显著改善了Cobb角和骨盆倾斜度(平均矫正分别为33.2°(55%)和11°(77%);p < 0.001)。在最后一次随访时,我们注意到额状面Cobb角矫正丢失(p < 0.01),而未观察到骨盆倾斜度有任何显著丢失(p > 0.9)。

结论

尽管总体并发症发生率为35%(其中一半为机械并发症),但骨盆T形结构与MCGRs联合治疗能提供令人满意的骨盆倾斜度矫正,中期维持良好,可能是早发性神经肌肉型脊柱侧弯手术治疗可考虑的一种方法。

证据水平

IV级;回顾性队列预后研究。

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