Department of Orthopedics, Hunan University of Medicine General Hospital, Huaihua, 418000, Hunan, People's Republic of China.
Department of Orthopedics, The Second Xiangya Hospital, Central South University, No. 139 Renmin Road, Changsha, 410011, Hunan, People's Republic of China.
Sci Rep. 2024 Oct 5;14(1):23214. doi: 10.1038/s41598-024-73492-8.
This retrospective study aimed to determine the incidence and risk factors for osteomyelitis recurrence and present our experiences in treating traumatic osteomyelitis in the lower leg and foot. We retrospectively reviewed data from 174 patients with distally based sural flaps for treating traumatic osteomyelitis with soft tissue defects in the lower leg and foot from November 2003 to February 2021. Possible risk factors for osteomyelitis recurrence were compared between the osteomyelitis control and recurrence groups. A total of 162 (93.1%) flaps survived uneventfully, while 12 (6.9%) flaps developed partial necrosis. Five patients had a bone defect with an average length of 5 cm. The free vascularized bone grafts were performed in two patients, and bone transportations were performed in three patients. All patients were followed up with an average period of 72.8 months. There were 152 patients (87.4%) in control group and 22 patients (12.6%) in recurrence group. The recurrence rates of osteomyelitis were significantly higher when the patient's age was 40 years or more and the duration was 10 weeks or more (P < 0.05). Cierny-Mader (C-M) classification type IV osteomyelitis was also significantly associated with osteomyelitis recurrence (p = 0.049). This flap combined with appropriate osteomyelitis treatment was an effective method to treat traumatic osteomyelitis of lower leg and foot with a soft tissue defect. Both patient age ≥ 40 years old and C-M type IV osteomyelitis were nonnegligible risk factors for osteomyelitis recurrence.
本回顾性研究旨在确定骨髓炎复发的发生率和危险因素,并介绍我们在治疗小腿和足部创伤性骨髓炎方面的经验。我们回顾性分析了 2003 年 11 月至 2021 年 2 月期间,174 例应用腓肠神经营养血管皮瓣治疗小腿和足部伴有软组织缺损的创伤性骨髓炎患者的资料。比较了骨髓炎对照组和复发组之间骨髓炎复发的可能危险因素。162 例(93.1%)皮瓣无并发症存活,12 例(6.9%)皮瓣发生部分坏死。5 例患者有 5cm 平均长度的骨缺损。2 例患者行游离带血管骨移植,3 例患者行骨搬运术。所有患者平均随访 72.8 个月。对照组 152 例(87.4%),复发组 22 例(12.6%)。当患者年龄 40 岁或以上,病程 10 周或以上时,骨髓炎复发率显著升高(P<0.05)。Cierny-Mader(C-M)分类 IV 型骨髓炎也与骨髓炎复发显著相关(p=0.049)。该皮瓣联合适当的骨髓炎治疗是治疗小腿和足部伴有软组织缺损的创伤性骨髓炎的有效方法。患者年龄≥40 岁和 C-M 型 IV 型骨髓炎均是骨髓炎复发的不可忽视的危险因素。