• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利:CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验

经阴道射频消融术:一种治疗有生育意愿的有症状子宫肌瘤女性的治疗选择。

Transvaginal radiofrequency ablation: a therapeutic option for managing symptomatic uterine fibroids in women with reproductive desires.

作者信息

Marín Martínez Ma Eugenia, Cruz-Melguizo Sara, Vaquero Argüello Gema, Engels Calvo Virginia, De la Cruz Conty Ma Luisa, Pérez Medina Tirso

机构信息

Servicio de Ginecología, Hospital Universitario Puerta de Hierro Majadahonda, Madrid, Spain.

Servicio de Ginecología y Obstetricia, Hospital Universitario San Jorge-Jaca, Huesca, Spain.

出版信息

F S Rep. 2024 Jul 15;5(3):320-327. doi: 10.1016/j.xfre.2024.07.001. eCollection 2024 Sep.

DOI:10.1016/j.xfre.2024.07.001
PMID:39381652
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11456661/
Abstract

OBJECTIVE

To evaluate whether transvaginal radiofrequency (RF) ablation of fibroids is a technique that can be offered to women with reproductive desires.

DESIGN

Unicentric, prospective, observational study.

SETTING

University Hospital.

PATIENTS

Twenty-seven individuals who desired to become mothers after undergoing RF ablation for symptomatic fibroids.

INTERVENTIONS

Transvaginal RF ablation for symptomatic fibroids with a maximum total volume of 145 cm.

MAIN OUTCOME MEASURES

The reduction in the size of the fibroids, improvement of symptoms, and reproductive outcomes during the 24 months after the ablation. For patients who achieved pregnancy, we assessed the type of conception, course of gestation, type of delivery, neonatal outcomes, and occurrence of both maternal and fetal complications.

RESULTS

A statistically significant reduction in symptoms related to the fibroids 6 months after the ablation was demonstrated through the implementation of the Symptom Severity Scale. No patient required hospitalization after the procedure, and on average from the third day after intervention, they resumed their work activities without the need for analgesics. Among those patients who attempted pregnancy during the 24-month follow-up period, 73.68 % (14/19) achieved motherhood. There were no cases of uterine rupture, premature birth, or intrauterine fetal death.

CONCLUSIONS

Radiofrequency ablation for fibroids seems to be a promising, safe, and low-complexity alternative that does not appear to interfere with the development of a normal term gestation.

摘要

目的

评估经阴道射频消融治疗子宫肌瘤是否是一种可供有生育意愿的女性选择的技术。

设计

单中心、前瞻性观察性研究。

地点

大学医院。

患者

27名因有症状的子宫肌瘤接受射频消融治疗后希望成为母亲的个体。

干预措施

对最大总体积为145立方厘米的有症状子宫肌瘤进行经阴道射频消融。

主要观察指标

消融后24个月内子宫肌瘤大小的缩小、症状的改善以及生殖结局。对于成功怀孕的患者,我们评估了受孕类型、妊娠过程、分娩类型、新生儿结局以及母婴并发症的发生情况。

结果

通过症状严重程度量表的实施,证实消融后6个月与子宫肌瘤相关的症状有统计学意义的减轻。术后无患者需要住院,平均从干预后第三天起,她们无需使用镇痛药即可恢复工作活动。在24个月随访期内尝试怀孕的患者中,73.68%(14/19)成功受孕。无子宫破裂、早产或宫内胎儿死亡病例。

结论

子宫肌瘤射频消融似乎是一种有前景、安全且低复杂性的替代方法,似乎不会干扰足月妊娠的正常发展。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f5f3/11456661/9aaf565c7e01/gr2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f5f3/11456661/fb034deab587/gr1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f5f3/11456661/9aaf565c7e01/gr2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f5f3/11456661/fb034deab587/gr1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f5f3/11456661/9aaf565c7e01/gr2.jpg

相似文献

1
Transvaginal radiofrequency ablation: a therapeutic option for managing symptomatic uterine fibroids in women with reproductive desires.经阴道射频消融术:一种治疗有生育意愿的有症状子宫肌瘤女性的治疗选择。
F S Rep. 2024 Jul 15;5(3):320-327. doi: 10.1016/j.xfre.2024.07.001. eCollection 2024 Sep.
2
Ultrasound-guided transvaginal radiofrequency ablation of uterine fibroids assisted by virtual needle tracking system: a preliminary study.超声引导经阴道射频消融子宫肌瘤辅助虚拟针跟踪系统:初步研究。
Int J Hyperthermia. 2019 Jan 1;35(1):97-104. doi: 10.1080/02656736.2018.1479778. Epub 2018 Jul 17.
3
Uterine Myoma Position-based Radiofrequency Ablation (UMP-b RFA): 36 months follow-up clinical outcomes.基于子宫肌瘤位置的射频消融术(UMP-b RFA):36 个月的临床随访结果。
Eur J Obstet Gynecol Reprod Biol. 2023 Feb;281:23-28. doi: 10.1016/j.ejogrb.2022.12.006. Epub 2022 Dec 6.
4
A Prospective Intervention Trial on Tailored Radiofrequency Ablation of Uterine Myomas.前瞻性子宫平滑肌瘤射频消融个体化干预试验。
Medicina (Kaunas). 2020 Mar 12;56(3):122. doi: 10.3390/medicina56030122.
5
The FAST-EU trial: 12-month clinical outcomes of women after intrauterine sonography-guided transcervical radiofrequency ablation of uterine fibroids.FAST-EU试验:子宫肌瘤经宫颈超声引导下射频消融术后女性的12个月临床结局
Gynecol Surg. 2016;13:27-35. doi: 10.1007/s10397-015-0915-3. Epub 2015 Sep 28.
6
Ultrasound-Guided High Intensity Focused Ultrasound Ablation for Symptomatic Uterine Fibroids: Preliminary Clinical Experience.超声引导高强度聚焦超声消融治疗症状性子宫肌瘤:初步临床经验。
Ultraschall Med. 2020 Oct;41(5):550-556. doi: 10.1055/a-0891-0729. Epub 2019 Jun 25.
7
Efficacy, Complications, and Factors Predictive of Response to Treatment with Transvaginal Radiofrequency Ablation for Symptomatic Uterine Myomas.经阴道射频消融治疗症状性子宫肌瘤的疗效、并发症及影响疗效的相关因素。
J Minim Invasive Gynecol. 2022 Jun;29(6):743-752. doi: 10.1016/j.jmig.2022.01.011. Epub 2022 Jan 26.
8
Comparison between radiofrequency ablation combined with mifepristone and radiofrequency ablation for large uterine fibroids.射频消融联合米非司酮与射频消融治疗大型子宫肌瘤的比较。
Int J Hyperthermia. 2021;38(1):777-780. doi: 10.1080/02656736.2021.1922763.
9
Ultrasound-guided transvaginal radiofrequency myolysis for symptomatic uterine myomas.超声引导下经阴道射频消融治疗有症状的子宫肌瘤
Eur J Obstet Gynecol Reprod Biol. 2014 Jun;177:38-43. doi: 10.1016/j.ejogrb.2014.03.017. Epub 2014 Mar 29.
10
The management of uterine leiomyomas.子宫平滑肌瘤的管理
J Obstet Gynaecol Can. 2015 Feb;37(2):157-178. doi: 10.1016/S1701-2163(15)30338-8.

本文引用的文献

1
Pregnancy Outcomes After Laparoscopic Radiofrequency Ablation of Uterine Leiomyomas Compared With Myomectomy.腹腔镜射频消融子宫肌瘤与子宫肌瘤剔除术后的妊娠结局比较。
Obstet Gynecol. 2024 May 1;143(5):612-618. doi: 10.1097/AOG.0000000000005548. Epub 2024 Mar 1.
2
Complications of transvaginal radiofrequency ablation of fibroids: A 5-year experience.经阴道射频消融治疗子宫肌瘤的并发症:5年经验总结
Eur J Obstet Gynecol Reprod Biol X. 2023 Oct 10;20:100244. doi: 10.1016/j.eurox.2023.100244. eCollection 2023 Dec.
3
Risk of hysterectomy at the time of myomectomy: an underestimated surgical risk.
子宫肌瘤剔除术中的子宫切除风险:被低估的手术风险。
Fertil Steril. 2024 Jan;121(1):107-116. doi: 10.1016/j.fertnstert.2023.09.017. Epub 2023 Sep 28.
4
Myomectomy in infertile women: More harm than good?子宫肌瘤剔除术对不孕女性:弊大于利?
Front Surg. 2023 Apr 17;10:1151901. doi: 10.3389/fsurg.2023.1151901. eCollection 2023.
5
Pregnancy Outcomes After Transcervical Radiofrequency Ablation of Uterine Fibroids with the Sonata System.使用索纳塔系统经宫颈射频消融子宫肌瘤后的妊娠结局
J Gynecol Surg. 2022 Jun 1;38(3):207-213. doi: 10.1089/gyn.2021.0136. Epub 2022 Jun 13.
6
Radiofrequency Ablation of Uterine Myomas and Pregnancy Outcomes: An Updated Review of the Literature.射频消融子宫肌瘤与妊娠结局:文献的最新回顾。
J Minim Invasive Gynecol. 2022 Jun;29(6):709-715. doi: 10.1016/j.jmig.2022.01.015. Epub 2022 Feb 2.
7
Efficacy, Complications, and Factors Predictive of Response to Treatment with Transvaginal Radiofrequency Ablation for Symptomatic Uterine Myomas.经阴道射频消融治疗症状性子宫肌瘤的疗效、并发症及影响疗效的相关因素。
J Minim Invasive Gynecol. 2022 Jun;29(6):743-752. doi: 10.1016/j.jmig.2022.01.011. Epub 2022 Jan 26.
8
Conservative Management of Uterine Fibroid-Related Heavy Menstrual Bleeding and Infertility: Time for a Deeper Mechanistic Understanding and an Individualized Approach.子宫肌瘤相关月经过多和不孕症的保守治疗:深入理解机制并采取个体化方法的时候了。
J Clin Med. 2021 Sep 26;10(19):4389. doi: 10.3390/jcm10194389.
9
Uterine Fibroids and Infertility.子宫肌瘤与不孕
Diagnostics (Basel). 2021 Aug 12;11(8):1455. doi: 10.3390/diagnostics11081455.
10
Time to conceive after myomectomy: should we advise a minimum time interval? A systematic review.子宫肌瘤剔除术后妊娠时间:我们是否应该建议一个最小时间间隔?系统综述。
Reprod Biomed Online. 2021 Sep;43(3):543-552. doi: 10.1016/j.rbmo.2021.05.016. Epub 2021 May 30.