Safdar Ahmad, Young Laura, Khatri Jaikirshan
Cleveland Clinic Foundation, Cleveland, Ohio, USA.
Cleveland Clinic, Cleveland, Ohio, USA.
Catheter Cardiovasc Interv. 2024 Dec;104(7):1442-1446. doi: 10.1002/ccd.31262. Epub 2024 Oct 9.
This study highlights the prevalence and conservative management strategies of iatrogenic ascending aortic dissection after percutaneous intervention (PCI) of chronic total occlusion (CTO).
Retrospective analysis on patients who underwent CTO PCI from one medical center from 2020 to 2022 was performed by two operators. Data was obtained from the Prospective Global Registry for the Study of CTO database.
Out of 318 patients, there were six reported cases of iatrogenic ascending aortic dissection. The causes of dissection included guiding catheter trauma, antegrade injection, two retrograde injection, and two cases of balloon rupture after lithotripsy. IVUS-guided stenting of the coronary back to the origin to seal the entry of the dissection flap occurred in two patients. All patients had a conservative management approach. No patient had to undergo urgent surgery.
While the incidence remains rare, complications, including aortic dissection, are more frequent in CTO PCI as compared to non-CTO PCI. IVUS can be used to complete coronary intervention so long as the patient remains clinically and hemodynamically stable. Patients should have formal imaging with either transesophageal echocardiogram or computed tomography angiography. The outcomes of patients who experience iatrogenic aortic dissection during CTO PCI with stable coronary disease seem to be better than in patients with acute coronary syndrome.
本研究强调了慢性完全闭塞病变(CTO)经皮介入治疗(PCI)后医源性升主动脉夹层的发生率及保守治疗策略。
由两名操作者对2020年至2022年在某医疗中心接受CTO PCI治疗的患者进行回顾性分析。数据来源于CTO前瞻性全球研究注册数据库。
在318例患者中,有6例报告的医源性升主动脉夹层病例。夹层的原因包括导引导管损伤、顺行注射、两次逆行注射以及两例碎石术后球囊破裂。两名患者采用血管内超声(IVUS)引导下将冠状动脉支架置入至起始处以封闭夹层瓣入口。所有患者均采用保守治疗方法。无一例患者需要接受急诊手术。
虽然发生率仍然很低,但与非CTO PCI相比,CTO PCI中包括主动脉夹层在内的并发症更为常见。只要患者临床和血流动力学稳定,IVUS可用于完成冠状动脉介入治疗。患者应接受经食管超声心动图或计算机断层血管造影的正规影像学检查。在患有稳定型冠心病的CTO PCI过程中发生医源性主动脉夹层的患者的预后似乎优于急性冠状动脉综合征患者。