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富血小板血浆治疗女性压力性尿失禁

Platelet-rich plasma for treatment of female stress urinary incontinence.

作者信息

Pourebrahimi Amirhossein, Khalili Anita, Behzadi Saleh, Eftekhari Behrad, Reyhani Helya, Larijani Amirhossein, Norouzi Naeim, Madani Ali Hamidi

机构信息

Department of Medicine, Guilan University of Medical Sciences, Rasht, Iran.

Student Research Committee, Rafsanjan University of Medical Sciences, Rafsanjan, Iran.

出版信息

Int Urol Nephrol. 2025 Feb;57(2):313-321. doi: 10.1007/s11255-024-04229-9. Epub 2024 Oct 10.

Abstract

INTRODUCTION AND OBJECTIVE

Stress urinary incontinence (SUI) poses a significant burden on affected individuals, impairing their quality of life and causing embarrassment due to involuntary urine leakage during activities such as sneezing or coughing. While conservative and surgical treatments exist, a subset of patients experiences persistent symptoms despite these interventions. This review provides insights into the potential role of platelet-rich plasma (PRP) as a therapeutic adjunct for patients with SUI that does not respond to conventional non-surgical or surgical treatments.

METHODS

We conducted a literature review of studies in English to evaluate PRP efficacy in managing SUI.

RESULTS

The studies conducted on PRP therapy suggest that it is an effective and safe treatment option for SUI in women. PRP injections, when used alone or in combination with other therapies, have shown significant improvements in SUI symptoms. Moreover, these studies indicate that PRP injections offer a less invasive and low-risk alternative to surgical procedures for managing SUI, which could lead to shorter recovery times.

CONCLUSION

The efficacy of PRP therapy is evidenced by significant reductions in SUI symptoms, as well as improvements in bladder function variables, without significant adverse effects reported. However, further research is necessary to establish the long-term effectiveness and safety of PRP therapy for managing SUI in diverse patient populations. Additionally, ongoing evaluations of PRP therapy in combination with other interventions will be essential for optimizing treatment outcomes and broadening the potential applications of PRP in the management of SUI.

摘要

引言与目的

压力性尿失禁(SUI)给受影响的个体带来了沉重负担,损害他们的生活质量,并在打喷嚏或咳嗽等活动中因不自主漏尿而导致尴尬。尽管存在保守和手术治疗方法,但仍有一部分患者在接受这些干预后症状持续存在。本综述深入探讨了富血小板血浆(PRP)作为一种治疗辅助手段,对常规非手术或手术治疗无效的SUI患者的潜在作用。

方法

我们对英文研究进行了文献综述,以评估PRP治疗SUI的疗效。

结果

关于PRP治疗的研究表明,它是女性SUI的一种有效且安全的治疗选择。单独使用或与其他疗法联合使用PRP注射,已显示出SUI症状有显著改善。此外,这些研究表明,PRP注射为治疗SUI的手术提供了一种侵入性较小、风险较低的替代方法,这可能会缩短恢复时间。

结论

PRP治疗的疗效体现在SUI症状显著减轻以及膀胱功能变量改善上,且未报告明显不良反应。然而,有必要进一步研究以确定PRP治疗在不同患者群体中管理SUI的长期有效性和安全性。此外,对PRP治疗与其他干预措施联合使用的持续评估对于优化治疗效果以及扩大PRP在SUI管理中的潜在应用至关重要。

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