Department of Dermatology, Faculty of Medicine, Balikesir University, Balikesir, Turkey.
Department of Anatomy, Faculty of Medicine, Balikesir University, Balikesir, Turkey.
Med Sci Monit. 2024 Oct 15;30:e945935. doi: 10.12659/MSM.945935.
BACKGROUND Chronic urticaria (CU) is a skin condition causing itchy hives that can significantly impact quality of life. While medications like omalizumab can help, some patients may seek additional relief. This study aimed to investigate the potential benefits of acupuncture, a traditional Chinese medicine practice, as an adjunctive therapy alongside omalizumab for CU patients. MATERIAL AND METHODS We enrolled 31 CU patients who received acupuncture in addition to omalizumab (study group) and 30 CU patients who received omalizumab only (controls). Mean scores of each CU-Quality of life (QoL) and urticaria control test (UCT) scores after acupuncture were compared with the pre-acupuncture scores and with the scores of the controls. RESULTS There was no significant difference in mean food limitation, symptom embarrassment, cosmetics, and sports scores before and after acupuncture (P>0.005). Other CU-QoL scores were significantly lower after acupuncture compared to pre-acupuncture scores (P<0.005). Mean total CU-QoL score was significantly lower (P<0.001) and mean UCT score was significantly higher (P=0.001) after acupuncture compared to pre-acupuncture scores. There was no significant difference in free time, falling asleep, waking up at night, tiredness, concentration, symptom embarrassment, public embarrassment, cosmetics, clothing limitation, and sports scores between the acupuncture and control groups (P>0.005). Other CU-QoL scores were significantly lower in the acupuncture group compared to the controls (P<0.005). Mean total CU-QoL score was significantly lower (P=0.006) and mean UCT score was significantly higher (P<0.001) in acupuncture group compared to the controls. CONCLUSIONS Acupuncture is an effective adjunctive therapy for CU patients already receiving omalizumab, and can improve quality of life and disease control in these patients.
慢性荨麻疹（CU）是一种导致瘙痒性荨麻疹的皮肤疾病，可显著影响生活质量。虽然奥马珠单抗等药物可以提供帮助，但有些患者可能会寻求额外的缓解。本研究旨在探讨针刺作为奥马珠单抗辅助治疗 CU 患者的潜在益处。
我们招募了 31 名接受针刺加奥马珠单抗（研究组）和 30 名仅接受奥马珠单抗（对照组）的 CU 患者。比较针刺前后 CU 生活质量问卷（CU-QoL）和荨麻疹控制测试（UCT）评分的平均值，并与对照组进行比较。
针刺前后食物限制、症状尴尬、化妆品和运动评分的平均值无显著差异（P>0.005）。其他 CU-QoL 评分在针刺后显著低于针刺前（P<0.005）。针刺后总 CU-QoL 评分显著降低（P<0.001），UCT 评分显著升高（P=0.001），与针刺前相比。针刺组和对照组在自由时间、入睡、夜间醒来、疲劳、注意力、症状尴尬、公众尴尬、化妆品、穿衣受限和运动评分方面无显著差异（P>0.005）。针刺组的其他 CU-QoL 评分明显低于对照组（P<0.005）。针刺组的总 CU-QoL 评分显著降低（P=0.006），UCT 评分显著升高（P<0.001），与对照组相比。
针刺是接受奥马珠单抗治疗的 CU 患者的有效辅助治疗方法，可以改善这些患者的生活质量和疾病控制。
