Roller Victor, Ciuntu Angela, Țarcă Elena, Ionescu Nicolae Sebastian, Drăgoiu Teodora-Simina, Bernic Jana, Gudumac Eva, Ceban Emil, Mișina Ana, Băluțel Tatiana, Ignat Adriana, Fuior-Bulhac Liliana, Mîndru Dana Elena
Discipline of Pediatric Surgery, "Nicolae Testemițanu" State University of Medicine and Pharmacy, MD-2004 Chisinau, Moldova.
Department of Obstetrics and Gynaecology, Public Health Institution, Institute "Mother and Child", MD-2004 Chisinau, Moldova.
Diagnostics (Basel). 2024 Oct 8;14(19):2243. doi: 10.3390/diagnostics14192243.
Malformative uropathy in children is one of the most common pathological conditions, with an incidence of 5-14% in newborns. Recent research shows that even in the current conditions, they are often diagnosed only in the advanced stages, when Chronic Kidney Disease is already affirming. This study's objective is to identify urinary tract anomalies, including malformative uropathies in the prenatal stage, using imaging techniques, namely ultrasound of the pregnant uterus. Using prenatal ultrasonography of the pregnant uterus and postnatal clinical and paraclinical examination, we prospectively evaluated a cohort of fifty children with pyelectasia. We describe the demographic and pathological characteristics of patients diagnosed with renal-urinary abnormalities, as well as their postnatal management. A prenatal diagnosis made during the first 15 to 22 weeks of pregnancy enables the evaluation of early malformative uropathies and the determination of the best time to operate in order to minimize complications. When prenatal ultrasonography, fetal karyotype, tissue sample, and embryonic appendages work together, problems may be partially or entirely revealed by these methods due to mistakes made in imaging examinations. In the case of a pregnancy with an antenatal malformation detected, it is necessary for the delivery to take place in a clinic that can provide favorable services for the survival and investigation of the child born with malformative abnormalities.
儿童先天性泌尿系统疾病是最常见的病理状况之一,在新生儿中的发病率为5%至14%。最近的研究表明,即使在当前情况下,这些疾病往往在晚期才被诊断出来,此时慢性肾脏病已经确诊。本研究的目的是利用成像技术,即对妊娠子宫进行超声检查,在产前阶段识别泌尿系统异常,包括先天性泌尿系统疾病。通过对妊娠子宫进行产前超声检查以及产后临床和辅助检查,我们对50名肾盂扩张患儿进行了前瞻性评估。我们描述了被诊断为肾泌尿异常患者的人口统计学和病理特征,以及他们的产后管理情况。在妊娠的第15至22周进行产前诊断,能够评估早期先天性泌尿系统疾病,并确定最佳手术时间,以尽量减少并发症。当产前超声检查、胎儿核型分析、组织样本检查和胚胎附属物检查共同作用时,由于成像检查中的失误,这些方法可能会部分或全部揭示问题。如果检测到产前畸形的妊娠情况,分娩必须在能够为患有先天性异常的新生儿的存活和检查提供良好服务的诊所进行。