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贝内迪克特·奥古斯丁·莫雷尔(1809 - 1873):精神障碍遗传退化理论的创始人及精神病学生物学研究方法的先驱

Bénédict Augustin Morel (1809-1873): The Originator of the Degenerative Theory of the Heredity of Mental Disorders and the Pioneer of the Biological Approach to Psychiatry.

作者信息

Rosiou Eleni, Sgantzos Markos, Abatzoglou Grigoris, Papavramidou Niki

机构信息

Department of History of Medicine, School of Medicine, Aristotle University of Thessaloniki, Thessaloniki, GRC.

Department of Morphology, School of Medicine, University of Thessaly, Larissa, GRC.

出版信息

Cureus. 2024 Sep 16;16(9):e69523. doi: 10.7759/cureus.69523. eCollection 2024 Sep.

Abstract

The concept of progressive hereditary degeneration, which significantly influenced medical, particularly psychiatric and in turn social thought of the second half of the 19th century, was articulated by Bénédict Augustin Morel. The distinguished French psychiatrist developed the theory of degeneration and created the nosological framework of the heredity of mental illness in order to explain the more frequent psychoses and nervous disorders. In the absence of patho-anatomical findings, Morel attributed these phenomena to hereditary causes. His theory was the first attempt to interpret insanity, mental disorders, and criminality, across generations, and formed the basis for the further development of psychiatry. It had a notable influence on many scientific disciplines of the time, such as criminology, anthropology, biology, and general pathology. It would later result in the emergence of eugenics, which raised several moral issues and would ultimately be used in many ways to justify segregation. Morel was mainly influenced by the monogenetic degenerative theory and believed that social progress could be achieved by the coupling of psychiatry, a social medicine, with philosophy and Christianity.

摘要

本尼迪克特·奥古斯汀·莫雷尔提出了进行性遗传性退化的概念,这一概念对19世纪下半叶的医学,尤其是精神病学以及相应的社会思想产生了重大影响。这位杰出的法国精神病学家发展了退化理论,并创建了精神疾病遗传的疾病分类框架,以解释较为常见的精神病和神经疾病。在缺乏病理解剖学发现的情况下,莫雷尔将这些现象归因于遗传因素。他的理论是首次尝试跨代解释精神错乱、精神障碍和犯罪行为,并为精神病学的进一步发展奠定了基础。它对当时的许多科学学科产生了显著影响,如犯罪学、人类学、生物学和普通病理学。后来它导致了优生学的出现,这引发了一些道德问题,并最终在许多方面被用来为隔离行为辩护。莫雷尔主要受到单基因退化理论的影响,并认为社会进步可以通过作为社会医学的精神病学与哲学和基督教的结合来实现。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d4bd/11482047/3833ba2b1d11/cureus-0016-00000069523-i02.jpg

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