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侧颈部异位甲状腺乳头状癌:一例罕见病例报告。

Lateral neck ectopic papillary thyroid carcinoma: A rare case report.

作者信息

Ibrahim Miray, Attaf Ram, Alhaj Saleh Mohammed, Najjoum Hazar

机构信息

Faculty of Medicine, Al Andalus University for Medical Sciences, Tartous, Syria.

出版信息

Int J Surg Case Rep. 2024 Dec;125:110496. doi: 10.1016/j.ijscr.2024.110496. Epub 2024 Oct 22.

Abstract

INTRODUCTION

Ectopic thyroid tissue (ETT) occurs due to abnormal embryogenesis of the thyroid gland. Ectopic thyroid tissue is susceptible to all the processes that affect normal thyroid tissue, including malignant transformation. Malignancy of ectopic thyroid tissue is known as the exceedingly rare phenomenon of ectopic thyroid carcinoma (ETC).

PRESENTATION OF CASE

A 97-year old female presented with an ulcerated, hemorrhagic lateral neck mass that had been present for years prior to her visit. The mass was initially misdiagnosed as a haemangioma. During the surgical procedure, the operating surgeons discovered hallmark signs pointing towards malignancy. Histopathology of a biopsy taken from the mass confirmed the diagnosis of ectopic thyroid carcinoma (ETC). The patient was discharged in good condition and did not require further intervention.

DISCUSSION

The presence of ectopic thyroid carcinoma in the lateral neck is an extremely scarce finding. Medical literature details multiple modalities of diagnosis. We discuss similar cases and provide a comparison of currently applied diagnostic and therapeutic measures.

CONCLUSION

Thus far, no consensus has been reached regarding the optimal treatment or diagnosis of ectopic thyroid cancer, mainly due to their scarcity within the literature. As with most malignancies, early diagnosis is of great importance in order to ensure better outcomes. Individualised treatment options remain the cornerstone of the treatment of ETCs. More research is needed to outline practical tests to calibrate treatment in future cases.

摘要

引言

异位甲状腺组织(ETT)是由于甲状腺胚胎发育异常而产生的。异位甲状腺组织易受所有影响正常甲状腺组织的过程影响,包括恶性转化。异位甲状腺组织的恶性肿瘤被称为极其罕见的异位甲状腺癌(ETC)。

病例介绍

一名97岁女性因颈部外侧有一个溃疡、出血性肿块前来就诊,该肿块在她就诊前已存在多年。该肿块最初被误诊为血管瘤。在手术过程中,外科医生发现了指向恶性肿瘤的标志性体征。从肿块上取下的活检组织的组织病理学检查证实了异位甲状腺癌(ETC)的诊断。患者出院时情况良好,无需进一步干预。

讨论

颈部外侧出现异位甲状腺癌是一种极其罕见的发现。医学文献详细介绍了多种诊断方法。我们讨论了类似病例,并对目前应用的诊断和治疗措施进行了比较。

结论

迄今为止,关于异位甲状腺癌的最佳治疗或诊断尚未达成共识,主要是因为其在文献中较为罕见。与大多数恶性肿瘤一样,早期诊断对于确保更好的治疗效果非常重要。个体化的治疗方案仍然是异位甲状腺癌治疗的基石。需要更多的研究来制定实际的检测方法,以便在未来的病例中校准治疗方案。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/35e5/11542042/6381db9c6198/gr1.jpg

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