脓毒症老年患者中白蛋白校正阴离子间隙与死亡率之间的关联。
Association between albumin corrected anion gap and mortality in septic older adults.
作者信息
Zhou Qiang, Miao Yuxiu, Wang Pengfei, Li Fenghua, Li Jianing, Li Na
机构信息
Department of Orthopedic Surgery, Hekou District People's Hospital, Dongying City, Shandong Province, China.
Department of Operating Theatre, Dongying People's Hospital (Dongying Hospital of Shandong Provincial Hospital Group), Shandong Province, China.
出版信息
Geriatr Nurs. 2024 Nov-Dec;60:580-585. doi: 10.1016/j.gerinurse.2024.10.022. Epub 2024 Oct 29.
OBJECTIVES
This study aimed to investigate the association between albumin corrected anion gap (ACAG) and 30-day mortality in septic older adults.
METHODS
In this study, multivariate Cox regression models and Kaplan-Meier analysis were employed to evaluate the correlation between ACAG and 30-day mortality in septic older adults.
RESULTS
After adjustment for potential confounders, each 1 mmol/L increase in ACAG was associated with a 6% increase in 30-day mortality (HR, 1.06 [1.03-1.08], P < 0.001). Higher levels of ACAG in septic older adults were associated with lower 30-day survival rates based on Kaplan-Meier analysis.
CONCLUSIONS
This study observed a significant correlation between higher ACAG and 30-day mortality in septic older adults, thus indicating the need for increased attention from clinicians for patients with higher ACAG levels.
目的
本研究旨在调查脓毒症老年患者中白蛋白校正阴离子间隙（ACAG）与30天死亡率之间的关联。
方法
在本研究中，采用多变量Cox回归模型和Kaplan-Meier分析来评估脓毒症老年患者中ACAG与30天死亡率之间的相关性。
结果
在对潜在混杂因素进行调整后，ACAG每增加1 mmol/L，30天死亡率增加6%（风险比，1.06 [1.03 - 1.08]，P < 0.001）。根据Kaplan-Meier分析，脓毒症老年患者中较高的ACAG水平与较低的30天生存率相关。
结论
本研究观察到脓毒症老年患者中较高的ACAG与30天死亡率之间存在显著相关性，因此表明临床医生需要对ACAG水平较高的患者给予更多关注。
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