Elhabash Saleem, Langhammer Nils, Fetzner Ulrich Klaus, Kröger Jan-Robert, Dimopoulos Ioannis, Begum Nehara, Borggrefe Jan, Gerdes Berthold, Surov Alexey
Klinik für Allgemein‑, Viszeral‑, Thorax- und Endokrine Chirurgie, Universitätsklinikum Minden, Ruhr-Universität Bochum, Hans-Nolte-Str. 1, 32429, Minden, Deutschland.
Universitätsinstitut für Radiologie, Neuroradiologie und Nuklearmedizin, Universitätsklinikum Minden, Ruhr-Universität Bochum, Hans-Nolte-Str. 1, 32429, Minden, Deutschland.
Chirurgie (Heidelb). 2025 Mar;96(3):213-221. doi: 10.1007/s00104-024-02189-5. Epub 2024 Oct 29.
Screening of nutritional status of cancer patients plays a crucial role in the perioperative management and is mandatory for the certification of oncological centers by the German Cancer Society (DKG). The available screening tools do not differentiate between muscle and adipose tissue. Recent advances in computed tomography (CT) and magnetic resonance imaging (MRI) as well as the automatic picture archiving communication system (PACS) imaging analysis by high performance reconstruction systems have recently enabled a detailed analysis of adipose tissue and muscle quality. Rapidly growing evidence shows that body composition parameters, especially reduced muscle mass, are associated with adverse outcomes in cancer patients and have been reported to negatively affect overall survival (OS), disease-free survival (DFS), toxicity associated with chemotherapy and surgical complications. In this article, we summarize the recent literature and present the clinical influence of body composition in oncological visceral diseases.
癌症患者营养状况筛查在围手术期管理中起着至关重要的作用，并且是德国癌症协会（DKG）认证肿瘤中心的必备条件。现有的筛查工具无法区分肌肉和脂肪组织。计算机断层扫描（CT）和磁共振成像（MRI）的最新进展，以及高性能重建系统对自动图像存档通信系统（PACS）成像的分析，最近使得对脂肪组织和肌肉质量进行详细分析成为可能。越来越多的证据表明，身体成分参数，尤其是肌肉量减少，与癌症患者的不良预后相关，并且据报道会对总生存期（OS）、无病生存期（DFS）、化疗相关毒性和手术并发症产生负面影响。在本文中，我们总结了近期文献，并阐述了身体成分在肿瘤性内脏疾病中的临床影响。
