Miller Darby D, Wagner Isabella V, Ten Hulzen Richard D, Dorairaj Syril, Mashayekhi Arman, Krambeer Chelsey, Boopathiraj Nithya, Stewart Michael
Ophthalmology, Mayo Clinic, Jacksonville, USA.
Opthalmology, Mayo Clinic, Jacksonville, USA.
Cureus. 2024 Sep 29;16(9):e70455. doi: 10.7759/cureus.70455. eCollection 2024 Sep.
Topical anesthetics for control of pain from corneal abrasions can cause drug-related toxicity that delays corneal healing. This report documents three cases where topical anesthetic drops were prescribed in the emergency department for pain control, after which patients developed persistent ocular pain, epithelial toxicity with impaired healing, and significant loss of vision. On consultation with the ophthalmology service, each patient was instructed to discontinue the topical anesthetic drops but to continue topical antibiotics. Soon thereafter, symptoms resolved, and the corneas healed within 72 hours. This report emphasizes the harm that can result from injudicious and/or unmonitored use of topical anesthetics for corneal abrasions. We advise emergency medicine and primary care providers against providing topical anesthetics to patients with corneal abrasions.
用于控制角膜擦伤疼痛的局部麻醉药可导致与药物相关的毒性，从而延迟角膜愈合。本报告记录了3例在急诊科因疼痛控制而开具局部麻醉滴眼液的病例，之后患者出现持续性眼痛、上皮毒性伴愈合受损以及严重视力丧失。在咨询眼科服务部门后，指导每位患者停用局部麻醉滴眼液，但继续使用局部抗生素。此后不久，症状消失，角膜在72小时内愈合。本报告强调了对角膜擦伤不当和/或无监测使用局部麻醉药可能造成的危害。我们建议急诊医学和初级保健提供者不要为角膜擦伤患者提供局部麻醉药。
