Pu Xingxiao, Geng Chengkui, Xiao Weiping, Gu Shao, Wang Daxing, Liu Chengwei, Li Haifeng, Liu Bailian
Department of Orthopedics, Yan'an Hospital Affiliated to Kunming Medical University, Kunming, 650051, Yunnan, P.R. China.
Department of Orthopedics, West China Hospital, Orthopedic Research Institute, Sichuan University, Chengdu, P.R. China.
Eur Spine J. 2025 Jan;34(1):17-26. doi: 10.1007/s00586-024-08532-y. Epub 2024 Oct 30.
The study aims to investigate the correlations between the T score, Hounsfield units (HU) value, and vertebral bone quality (VBQ) score, and to compare their discrimination capability for patients with osteoporotic vertebral compression fracture (OVCF).
One hundred and sixty-three eligible participants were enrolled (49 OVCF group,114 non-OVCF group). The T score, HU value, and VBQ score were collected retrospectively. Then, those three parameters were compared between the OVCF and non-OVCF groups and the correlations among the three were assessed. Finally, the discrimination capability of those parameters was compared by the receiver operating characteristic (ROC) curves.
The OVCF group showed a lower T score, lower HU value, and higher VBQ score (all P < 0.001) than the non-OVCF group. Correlations were observed among the T score, HU value, and VBQ score (all P < 0.001, HU VS. mean T score, r = 0.66; HU VS. minimum T score, r = 0.67; VBQ VS. mean/ minimum T score, r=-0.33; VBQ VS. HU, r=-0.45). The HU value indicated the maximum area under curve (AUC), followed by the VBQ score and then the T score. Moreover, the AUC of combining the VBQ score and the HU value was similar to that of the HU value.
Both the HU value and the VBQ score had superior discrimination capability for patients with OVCF compared to the T score, especially for the HU value. For patients with routinely performed lumbar MRI or CT scans, the HU value or the VBQ score may provide alternative options for assessing the bone condition.
本研究旨在探讨T值、亨氏单位（HU）值与椎体骨质量（VBQ）评分之间的相关性，并比较它们对骨质疏松性椎体压缩骨折（OVCF）患者的鉴别能力。
招募了163名符合条件的参与者（49名OVCF组，114名非OVCF组）。回顾性收集T值、HU值和VBQ评分。然后，比较OVCF组和非OVCF组之间的这三个参数，并评估三者之间的相关性。最后，通过受试者工作特征（ROC）曲线比较这些参数的鉴别能力。
与非OVCF组相比，OVCF组的T值更低、HU值更低、VBQ评分更高（均P < 0.001）。观察到T值、HU值和VBQ评分之间存在相关性（均P < 0.001，HU与平均T值，r = 0.66；HU与最低T值，r = 0.67；VBQ与平均/最低T值，r=-0.33；VBQ与HU，r=-0.45）。HU值显示出最大的曲线下面积（AUC），其次是VBQ评分，然后是T值。此外，VBQ评分和HU值相结合的AUC与HU值相似。
与T值相比，HU值和VBQ评分对OVCF患者具有更好的鉴别能力，尤其是HU值。对于常规进行腰椎MRI或CT扫描的患者，HU值或VBQ评分可能为评估骨状况提供替代选择。
