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经外周静脉导入中心静脉导管相关的主动脉瓣感染性心内膜炎合并大量主动脉瓣反流需急诊手术:一例报告

Broviac Catheter-Related Aortic Valve Infective Endocarditis Complicated With Massive Aortic Regurgitation Requiring Emergency Surgery: A Case Report.

作者信息

Wilawer Małgorzata, Elikowski Waldemar, Fertała Natalia, Włodarski Arkadiusz, Szczęśniewski Patryk, Ratajska Paulina Anna, Bugajski Paweł

机构信息

Department of Internal Medicine, Józef Struś Hospital, Poznań, Poland.

Intensive Care Unit (ICU), Józef Struś Hospital, Poznań, Poland.

出版信息

Case Rep Infect Dis. 2024 Oct 24;2024:1093820. doi: 10.1155/2024/1093820. eCollection 2024.

Abstract

Broviac catheter is a type of central venous catheter (CVC) used for long-term parenteral nutrition in specific patients, e.g., diagnosed with intestinal failure as short bowel syndrome (SBS). The way of the catheter insertion is conceived to minimalize the risk of infections. However, CVC-related blood stream infections (CVC-BSIs), including infective endocarditis (IE), remain most important complications associated with Broviac catheter. stands out as a prevalent pathogen. The increasing number of CVCs results in an increased incidence of healthcare-associated IE. Complete parenteral treatment is an independent risk that increases the likelihood of IE. Treatment of IE is mainly based on antibiotic therapy, but in certain cases, surgical treatment is needed. A 71-year-old female with SBS who had been receiving total parenteral nutrition through the Broviac catheter for several months was admitted in a serious condition with significant weakness, increasing shortness of breath, deteriorating cough, fever, low blood pressure, and heart palpitations. Echocardiography revealed severe aortic valve IE with a large, longitudinal, highly mobile vegetation (up to 40 mm) and massive aortic regurgitation with pulmonary edema. Fast pathogen detection in the patients' blood () was obtained using PCR-based multiplex test. Due to life-threatening conditions, emergency surgery with aortic valve replacement was performed. Consistent rehabilitation resulted in good condition achievement. Follow-up echocardiography showed normal function of the aortic valve bioprosthesis. The use of CVC, including Broviac catheter, is associated with an increased risk of infections, including IE. Treatment-resistant severe HF complicating IE requires emergency surgery.

摘要

布罗维阿克导管是一种中心静脉导管(CVC),用于特定患者的长期肠外营养,例如,被诊断为短肠综合征(SBS)导致肠衰竭的患者。导管插入方式旨在将感染风险降至最低。然而,与中心静脉导管相关的血流感染(CVC-BSIs),包括感染性心内膜炎(IE),仍然是与布罗维阿克导管相关的最重要并发症。 是一种常见病原体。中心静脉导管数量的增加导致医疗相关感染性心内膜炎的发病率上升。完全肠外治疗是增加感染性心内膜炎可能性的独立风险因素。感染性心内膜炎的治疗主要基于抗生素治疗,但在某些情况下,需要进行手术治疗。 一名71岁患有短肠综合征的女性,通过布罗维阿克导管接受了数月的全肠外营养,因病情严重入院,伴有明显虚弱、呼吸急促加重、咳嗽恶化、发热、低血压和心悸。超声心动图显示严重的主动脉瓣感染性心内膜炎,伴有一个大的、纵向的、高度活动的赘生物(长达40毫米)以及大量主动脉瓣反流伴肺水肿。使用基于聚合酶链反应的多重检测方法对患者血液进行快速病原体检测。由于病情危及生命,进行了主动脉瓣置换的急诊手术。持续的康复治疗使病情好转。随访超声心动图显示主动脉瓣生物假体功能正常。 使用包括布罗维阿克导管在内的中心静脉导管会增加包括感染性心内膜炎在内的感染风险。并发感染性心内膜炎的难治性严重心力衰竭需要急诊手术。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f198/11527529/faa796770f14/CRIID2024-1093820.001.jpg

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