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救命药物的危及生命反应:PCSK-9单克隆抗体严重不良反应的逐步处理方法

Life-Threatening Reaction to Lifesaving Medication: Stepwise Approach to Severe Adverse Reactions to PCSK-9 Monoclonal Antibodies.

作者信息

Bimal Tia, Szema Anthony, Pavlovic Maia, Karalis Dean, Gianos Eugenia

机构信息

Northwell, New Hyde Park, New York, Cardiovascular Institute, Lenox Hill Hospital, Northwell Health, New York, New York, USA.

Northwell, New Hyde Park, New York, Mather Hospital, Northwell Health, Port Jefferson, New York, USA.

出版信息

JACC Case Rep. 2024 Oct 2;29(19):102614. doi: 10.1016/j.jaccas.2024.102614.

Abstract

Typical side effects of proprotein convertase subtilisin/kexin type 9 monoclonal antibodies including influenza-like illness and injection site reactions, are minor and well tolerated. This case, however, highlights a less common but severe reaction, indicating the need for clinicians to understand and manage potential rare side effects noted with biologics.

摘要

前蛋白转化酶枯草溶菌素/克新9型单克隆抗体的典型副作用包括流感样疾病和注射部位反应,这些副作用较小且耐受性良好。然而,该病例突出了一种不太常见但严重的反应,表明临床医生需要了解和处理生物制剂中潜在的罕见副作用。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b840/11522809/4257bff45882/ga1.jpg

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