Salevitz Daniel, Payne Nicolette, Madura Grace, Lin Chung-Yon, Parker Kelly, Grimsby Gwen
Department of Urology, Mayo Clinic Arizona, Phoenix, AZ.
Mayo Clinic Alix School of Medicine, Phoenix, AZ.
Urology. 2025 Mar;197:149-155. doi: 10.1016/j.urology.2024.10.062. Epub 2024 Oct 30.
To examine current opioid prescribing and determine what clinical factors were associated with use of opioids after urologic surgery after a previous study from our institution found that education regarding opioid prescribing practices significantly decreased post-operative opioid prescriptions from 61% to 34% (P <.0001).
From 2017 to 2023, a questionnaire querying what medications were used for post-operative pain was administered to patients/families at a postoperative visit. Survey results and demographic factors were obtained via retrospective chart review. Fisher's exact and t tests compared patients who did and did not use opioids.
1630 patients' families completed a survey, with mean age 5.3 years, 95% male. Over the study period, 550 patients (34%) were prescribed opioids, and 474/1630 (29%) used opioids post-operatively. Patients who used opioids were significantly older (7 vs 4 years, P <.0001). Endoscopic surgery (P = .0005), buried penis/torsion/chordee repair (P <.0001), meatoplasty/skin bridge (P <.0001), and alternating acetaminophen and ibuprofen (P <.0001) were associated with decreased opioid use. Families of patients who used opioids had higher rates of calling the clinic (6% vs 2%, P = .0011) and visiting the Emergency Department (ED) with pain concerns (3% vs 0.7%, P = .002). In 2017, 63% of patients were prescribed opioids after surgery compared with 6% in 2023 (P <.0001).
Most pediatric urologic surgeries can be performed without outpatient post-operative opioids. After education, we decreased opioid prescribing to only 5% of patients. The patients who were prescribed opioids had higher rates of ED visits or calling the clinic nurses with pain concerns.
在我们机构之前的一项研究发现,关于阿片类药物处方实践的教育显著降低了术后阿片类药物处方率,从61%降至34%(P<0.0001)之后,本研究旨在检查当前的阿片类药物处方情况,并确定泌尿外科手术后使用阿片类药物与哪些临床因素相关。
2017年至2023年期间,在术后随访时向患者/家属发放了一份询问术后疼痛使用何种药物的问卷。通过回顾性病历审查获得调查结果和人口统计学因素。采用Fisher精确检验和t检验对使用和未使用阿片类药物的患者进行比较。
1630名患者家属完成了调查,平均年龄5.3岁,95%为男性。在研究期间,550名患者(34%)被开具了阿片类药物,474/1630(29%)的患者术后使用了阿片类药物。使用阿片类药物的患者年龄显著更大(7岁对4岁,P<0.0001)。内镜手术(P=0.0005)、埋藏阴茎/扭转/尿道下裂修复术(P<0.0001)、尿道口成形术/皮肤桥(P<0.0001)以及交替使用对乙酰氨基酚和布洛芬(P<0.0001)与阿片类药物使用减少相关。使用阿片类药物的患者家属致电诊所的比例更高(6%对2%,P=0.0011),因疼痛问题前往急诊科(ED)就诊的比例也更高(3%对0.7%,P=0.002)。2017年,63%的患者术后被开具阿片类药物,而2023年这一比例为6%(P<0.0001)。
大多数小儿泌尿外科手术可以在不使用门诊术后阿片类药物的情况下进行。经过教育后,我们将阿片类药物的处方率降至仅5%的患者。被开具阿片类药物的患者因疼痛问题前往急诊科就诊或致电诊所护士的比例更高。