Population Health Sciences Institute, Newcastle University, Newcastle Upon Tyne, United Kingdom; Newcastle University Centre for Cancer, Newcastle University, Newcastle Upon Tyne, United Kingdom.
Population Health Sciences Institute, Newcastle University, Newcastle Upon Tyne, United Kingdom.
Eur J Oncol Nurs. 2024 Dec;73:102696. doi: 10.1016/j.ejon.2024.102696. Epub 2024 Sep 23.
To explore the unmet supportive care needs of patients with advanced cancer receiving immuno-, biological and precision (IBP) therapies.
We conducted semi-structured interviews with: (1) adults diagnosed with advanced cancer (lung, colorectal, ovary, breast, renal, melanoma) treated with an IBP therapy (e.g. tyrosine kinase inhibitors, monoclonal antibodies, immunotherapy), for at least one month; (2) healthcare professionals involved in providing hospital care for patients receiving IBP therapies. Interviews were audio-recorded, transcribed and analysed using the Framework Analysis approach; the framework comprised of 11 domains of unmet need: activities of daily living, autonomy, economic, healthcare, information, physical, psychological, role, sexual, social; and an "other" category (to capture data relating to unmet needs that did not fit within pre the-defined domains).
Thirty-one patients and 22 healthcare professionals were interviewed. Ten domains of unmet needs (exceptions: spiritual, other) were evident in the data. Identified unmet needs related to: (1) utilising the IBP therapies (e.g. specific treatment side effects [physical domain], living long-term with uncertainty [psychological], others not understanding why they were not cured [social]; and (2) living with (advanced) cancer (e.g. retiring from work [role], loss of independence [autonomy]).
Patients with advanced cancer being treated with IBP therapies have a diverse range of often inter-related unmet needs. It is vital that healthcare professionals involved in the care of cancer patients using IBP therapies are alert to the unmet needs among this patient group. Interventions and services should be developed to address these needs.
探索接受免疫、生物和精准 (IBP) 治疗的晚期癌症患者未满足的支持性护理需求。
我们对以下人群进行了半结构化访谈：（1）接受 IBP 治疗（例如酪氨酸激酶抑制剂、单克隆抗体、免疫疗法）至少一个月的晚期癌症（肺癌、结直肠癌、卵巢癌、乳腺癌、肾癌、黑色素瘤）成人；（2）参与为接受 IBP 治疗的患者提供医院护理的医疗保健专业人员。访谈进行了录音、转录，并使用框架分析方法进行分析；框架包括 11 个未满足需求领域：日常生活活动、自主性、经济、医疗保健、信息、身体、心理、角色、性、社会；以及一个“其他”类别（用于捕获与未满足需求相关的数据，这些数据不符合预先定义的领域）。
对 31 名患者和 22 名医疗保健专业人员进行了访谈。数据中存在 10 个未满足需求领域（例外：精神，其他）。确定的未满足需求与：（1）使用 IBP 治疗相关（例如特定的治疗副作用[身体领域]，长期处于不确定状态[心理]，其他人不明白为什么他们没有被治愈[社会]；以及（2）与（晚期）癌症共存（例如从工作中退休[角色]，失去独立性[自主性]）。
接受 IBP 治疗的晚期癌症患者有各种各样的未满足需求，这些需求往往相互关联。参与使用 IBP 治疗癌症患者护理的医疗保健专业人员必须意识到这一患者群体的未满足需求。应开发干预措施和服务来满足这些需求。
