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不完全性右束支传导阻滞的特征与预后:一项流行病学研究

Characteristics and prognosis of incomplete right bundle branch block: an epidemiologic study.

作者信息

Liao Y L, Emidy L A, Dyer A, Hewitt J S, Shekelle R B, Paul O, Prineas R, Stamler J

出版信息

J Am Coll Cardiol. 1986 Mar;7(3):492-9. doi: 10.1016/s0735-1097(86)80458-2.

Abstract

A cohort of 1,960 white men aged 40 to 56 years without initial apparent heart disease and with 11 years of annual rest electrocardiograms and 20 year mortality data was followed in the Chicago Western Electric Company Study. Incomplete right bundle branch block was found in 134 men (6.8%) at entry. During follow-up, 222 men developed such block, an incidence rate of 13.6%. Left axis deviation of -30 degrees or less was more frequent in men with than in those without incomplete block at entry (8.2 versus 2.4%). Men with left axis deviation also had a higher incidence of incomplete right bundle branch block. Similarly, men developing incomplete block had a significantly greater risk of developing left axis deviation. The associations between incomplete block and left axis deviation were unrelated to age and body weight. Men with incomplete block had a significantly greater likelihood of developing complete right bundle branch block. The 11 year incidence rate of complete block was 5.1% for men with baseline incomplete block and 0.7% for those without. Complete block developed in 2 of 220 incident cases of incomplete block but in none of the 440 control men matched by age and duration of follow-up. Although incomplete right bundle branch block was not related to an increased risk of death in 20 years from coronary heart disease and cardiovascular diseases, the study data suggest that such block is frequently a manifestation of primary abnormality of the cardiac conduction system in middle-aged men.

摘要

在芝加哥西方电气公司的一项研究中,对1960名年龄在40至56岁之间、最初无明显心脏病、有11年年度静息心电图及20年死亡率数据的白人男性进行了随访。研究开始时,134名男性(6.8%)被发现存在不完全性右束支传导阻滞。随访期间,222名男性出现了这种阻滞,发病率为13.6%。研究开始时,存在不完全性右束支传导阻滞的男性中,电轴左偏-30度或更小的情况比无此阻滞的男性更常见(8.2%对2.4%)。电轴左偏的男性发生不完全性右束支传导阻滞的发生率也更高。同样,出现不完全性右束支传导阻滞的男性发生电轴左偏的风险显著更高。不完全性右束支传导阻滞与电轴左偏之间的关联与年龄和体重无关。存在不完全性右束支传导阻滞的男性发生完全性右束支传导阻滞的可能性显著更高。基线存在不完全性右束支传导阻滞的男性,11年完全性右束支传导阻滞的发病率为5.1%,无此情况的男性为0.7%。在220例不完全性右束支传导阻滞的新发病例中,有2例出现了完全性右束支传导阻滞,但在按年龄和随访时间匹配的440名对照男性中无一例发生。虽然不完全性右束支传导阻滞与20年内冠心病和心血管疾病死亡风险增加无关,但研究数据表明,这种阻滞在中年男性中常常是心脏传导系统原发性异常的一种表现。

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