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青少年特发性脊柱侧凸人群手术部位感染危险因素分析。

Analysis of adolescent idiopathic scoliosis population for Surgical Site Infection Risk Factors.

作者信息

Fletcher Jesse, Liu Xue-Cheng, Thometz John G

机构信息

Medical College of Wisconsin, United States.

Division of Pediatric Orthopaedics, Children's Wisconsin, Department of Orthopaedic Surgery, United States.

出版信息

J Orthop. 2024 Oct 13;62:66-69. doi: 10.1016/j.jor.2024.10.020. eCollection 2025 Apr.

Abstract

OBJECTIVE

The incidence of surgical site infection (SSI) in adolescent idiopathic scoliosis (AIS) patients undergoing surgical correction varies but is commonly reported between 0.5 and 6.7 %. The identification of modifiable risk factors is crucial to preventing these infections in the AIS population. Some potential modifiable risk factors include the use of stainless-steel implants, a larger volume of instrumentation and an increased volume of blood products transfused. However, evidence in support of these factors and others representing true risk for the development of SSI is limited and often varies. We aimed to determine the incidence of SSI in AIS undergoing primary scoliosis fusion at our hospital, and explore demographic and clinical variables in the development of SSI in AIS.

METHODS

This was a case control retrospective study. Patients aged 10-19 year-old that underwent posterior spinal fusion for initial correction of AIS at our hospital between the years 2012-2020 were eligible. Patients with any previous spine surgery or spine fracture were excluded. A descriptive analysis was then performed on the data.

RESULTS

Of the 334 patients on which data was collected, one SSI was identified resulting in an incidence of infection of 0.3 %. The largest ethnicity represented was Caucasian with 254 patients. The average age was 14.3 years with averaged follow-up of 6.6 years. The majority of patients (252) received implants composed of titanium and cobalt chrome. The average operation duration was 5 h and 7.7 min, and the average hospital stay was 4.2 days. The average amount of blood loss was 553 ml. Chlorhexidine wipes or some other antimicrobial preparation was used on 197 patients and betadine solution was used on 321.185 patients were recorded to have received either antibiotic-loaded allograft or antibiotic powder and 326 patients were recorded to have received intraoperative antibiotics.

CONCLUSIONS

The long term clinical follow up of our study and low incidence of infection provide additional evidence for the benefit of antimicrobial techniques and risk factor mitigation previously suggested in the literature for the prevention of SSI in AIS.

LEVEL OF EVIDENCE

Level III.

摘要

目的

接受手术矫正的青少年特发性脊柱侧凸(AIS)患者手术部位感染(SSI)的发生率各不相同,但普遍报道为0.5%至6.7%。识别可改变的风险因素对于预防AIS人群中的这些感染至关重要。一些潜在的可改变风险因素包括使用不锈钢植入物、更大体积的器械以及增加输血制品的量。然而,支持这些因素以及其他代表SSI发生真正风险的因素的证据有限且往往存在差异。我们旨在确定我院接受原发性脊柱侧凸融合术的AIS患者中SSI的发生率,并探讨AIS患者发生SSI时的人口统计学和临床变量。

方法

这是一项病例对照回顾性研究。2012年至2020年间在我院接受后路脊柱融合术以初步矫正AIS的10至19岁患者符合条件。排除既往有任何脊柱手术或脊柱骨折的患者。然后对数据进行描述性分析。

结果

在收集数据的334例患者中,发现1例SSI,感染发生率为0.3%。人数最多的种族是白种人,有254例患者。平均年龄为14.3岁,平均随访6.6年。大多数患者(252例)接受了由钛和钴铬制成的植入物。平均手术时间为5小时7.7分钟,平均住院时间为4.2天。平均失血量为553毫升。197例患者使用了氯己定湿巾或其他抗菌制剂,321例使用了碘伏溶液。记录显示185例患者接受了含抗生素的同种异体移植物或抗生素粉末,326例患者接受了术中抗生素治疗。

结论

我们研究的长期临床随访和低感染率为文献中先前提出的抗菌技术和降低风险因素对预防AIS患者SSI的益处提供了更多证据。

证据级别

三级。

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