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常规 HPV 疫苗接种:基于各国经验的接种策略思考。

Routine HPV vaccination: Reflection on delivery strategies based on countries' experiences.

机构信息

Centre for the Evaluation of Vaccination, University of Antwerp, Antwerp, Belgium.

Department of Infectious Disease Epidemiology, London School of Hygiene and Tropical Medicine, London, United Kingdom.

出版信息

Vaccine. 2024 Jul 11;42 Suppl 2:S37-S40. doi: 10.1016/j.vaccine.2023.09.009. Epub 2024 Nov 7.

Abstract

Despite the introduction of the human papillomavirus (HPV) vaccine in many low- and middle-income countries (LMICs), countries are still struggling to maintain HPV vaccination coverage and manage sustainable delivery strategies. This article explores the challenges and effective strategies for HPV vaccine delivery in LMICs, with a focus on reflecting upon current HPV vaccine delivery strategies in the World Health Organization (WHO) HPV vaccine introduction guidelines to align with practical implementation experiences. The article utilizes presentations and discussions from Coalition to Strengthen the HPV Immunization Community (CHIC) symposia, field experiences of program implementers who participated in the meeting and immunization expert opinions, to inform its findings. Several countries are spotlighted for their delivery strategies. These include routinized campaign mode vaccinations at schools in The Gambia, Zambia, and Ethiopia; routine health facility services in Tanzania, Kenya, and Maldives; and outreach strategies targeting out-of-school girls. By evaluating these diverse strategies, the article suggests a need to delve deeper and build an understanding of the routinized campaign mode of HPV vaccine delivery, and advocates for expanding the scope of delivery strategies and consequently updating the WHO HPV vaccine delivery guidelines in line with the evolving landscape of HPV vaccination delivery to ensure comprehensive, cost-effective, and sustainable programs in LMICs.

摘要

尽管在许多低收入和中等收入国家(LMICs)引入了人乳头瘤病毒(HPV)疫苗,但这些国家仍在努力维持 HPV 疫苗接种覆盖率并管理可持续的交付策略。本文探讨了在 LMICs 中提供 HPV 疫苗的挑战和有效策略,重点是反思世界卫生组织(WHO)HPV 疫苗接种指南中的当前 HPV 疫苗接种策略,以符合实际实施经验。本文利用 Coalition to Strengthen the HPV Immunization Community (CHIC) 研讨会的演讲和讨论、参加会议的方案实施者的现场经验以及免疫专家的意见来提供信息。一些国家因其提供策略而受到关注。这些策略包括冈比亚、赞比亚和埃塞俄比亚在学校进行常规的运动模式疫苗接种;坦桑尼亚、肯尼亚和马尔代夫在常规卫生机构提供服务;以及针对校外女孩的外展策略。通过评估这些不同的策略,本文建议需要更深入地研究和理解 HPV 疫苗接种的常规运动模式,并主张扩大提供策略的范围,从而更新 WHO 的 HPV 疫苗接种指南,以适应 HPV 疫苗接种不断发展的格局,确保在 LMICs 中开展全面、具有成本效益和可持续的计划。

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