Fay Felix, Straube Andreas, Ruscheweyh Ruth, Eren Ozan Emre
Klinik für Neurologie, Oberbayerisches Kopfschmerzzentrum, Klinikum Großhadern, Ludwig-Maximilians-Universität, München, Deutschland.
Neurologische Klinik und Poliklinik, LMU-Klinikum, Standort Großhadern, Marchioninistraße 15, 81377, München, Deutschland.
Nervenarzt. 2024 Dec;95(12):1124-1130. doi: 10.1007/s00115-024-01768-5. Epub 2024 Nov 12.
Visual snow is a disorder of visual perception that is manifested as a constant flickering or "TV-like" noise in the entire visual field. Visual snow syndrome (VSS) describes a combination with other additional visual symptoms, such as sensitivity to light, afterimages, night blindness and entoptic phenomena. Cases of VS have been described in the literature using a wide variety of terms, often misunderstood as persistent migraine aura. Established diagnostic criteria have existed for more than 10 years now; however, the pathophysiology is still incompletely understood. The exact prevalence also remains unknown and high numbers of unreported cases are suspected. This is the first detailed description of a cohort of VSS patients from Germany.
Patients with VSS from several studies conducted at our center were pooled and retrospectively evaluated with respect to demographic, epidemiological and clinical data.
In this study 66 patients with VSS were included (age 31.3 ± 8.3 years, 30 women). The most commonly associated visual symptoms were photophobia (67%) and afterimages (65%). Of the patients 36 (54%) had comorbid migraine of whom 25 (70%) had migraine with aura, 26 (39%) reported depressive symptoms and 32 (48%) symptoms of an anxiety disorder. Tinnitus was reported by 32 (48%) patients.
The characteristics of the German cohort described here are similar to other international descriptions. Due to the frequent psychological comorbidity there is still a risk of psychosomatic stigmatization.
视雪症是一种视觉感知障碍,表现为整个视野中持续闪烁或类似“电视画面”的噪点。视雪综合征(VSS)描述了一种伴有其他视觉症状的情况,如畏光、后像、夜盲和内视现象。文献中使用了各种各样的术语来描述VSS病例,这些病例常被误解为持续性偏头痛先兆。目前已有的诊断标准已存在10多年;然而,其病理生理学仍未完全明了。确切的患病率也仍然未知,且怀疑有大量未报告的病例。这是对来自德国的一组VSS患者的首次详细描述。
汇总了在我们中心进行的几项研究中的VSS患者,并对其人口统计学、流行病学和临床数据进行回顾性评估。
本研究纳入了66例VSS患者(年龄31.3±8.3岁,30名女性)。最常见的相关视觉症状是畏光(67%)和后像(65%)。36例(54%)患者合并偏头痛,其中25例(70%)为伴有先兆的偏头痛,26例(39%)报告有抑郁症状,32例(48%)有焦虑症症状。32例(48%)患者报告有耳鸣。
这里描述的德国患者队列的特征与其他国际描述相似。由于心理合并症常见,仍存在身心污名化的风险。