Zaman Zubia, Majid Zain
Dr. Ruth K. M. Pfau Civil Hospital Karachi, Civil Hospital Karachi, Karachi 74100, Sindh, Pakistan.
Department of Gastroenterology, Sindh Institute of Urology and Transplantation, Karachi 75500, Pakistan.
World J Gastrointest Pharmacol Ther. 2024 Nov 5;15(6):99226. doi: 10.4292/wjgpt.v15.i6.99226.
Inflammatory bowel disease (IBD) has a low prevalence in the Global South, including Pakistan. While genetics and gut flora, influenced by diet and the environment, can contribute to this, we are exploring the possibility of underdiagnosis. Lack of facilities trained in IBD, scarcity of medications, limited health insurance for specialist referral and the current epidemic of abdominal tuberculosis could be the cause. The increasing diagnosis of IBD among Pakistani immigrants and colorectal carcinoma among the young population might be the result of this. Timely referrals by primary care physicians to gastroenterologists, along with the growing use of newer technologies such as abdominal ultrasound for diagnosis can help mitigate the challenge of low or late diagnosis of this chronic condition.
炎症性肠病(IBD)在包括巴基斯坦在内的全球南方地区发病率较低。虽然受饮食和环境影响的遗传因素和肠道菌群可能导致这种情况,但我们正在探讨诊断不足的可能性。缺乏IBD相关培训设施、药物短缺、专科转诊的医疗保险有限以及当前腹部结核病的流行可能是原因所在。巴基斯坦移民中IBD诊断率的上升以及年轻人群中结直肠癌发病率的上升可能就是由此导致的。初级保健医生及时将患者转诊给胃肠病学家,以及越来越多地使用腹部超声等新技术进行诊断,有助于缓解这种慢性病诊断不足或诊断延迟的挑战。