伴有巩膜外扩展的脉络膜和睫状体黑色素瘤的预后因素。

Prognostic factors in choroidal and ciliary body melanomas with extrascleral extension.

作者信息

Pach J M, Robertson D M, Taney B S, Martin J A, Campbell R J, O'Brien P C

出版信息

Am J Ophthalmol. 1986 Mar 15;101(3):325-31. doi: 10.1016/0002-9394(86)90828-7.

Abstract

In a retrospective study, 50 (8.2%) of 610 patients with malignant melanoma of the ciliary body or choroid had extrascleral extension. Of 46 patients for whom follow-up data were available, 24 (52%) survived five years, 20 (42%) survived ten years, and 17 (37%) survived 15 years. Factors that seemed to affect survival significantly included intraocular tumor size and extraocular tumor size and location. Our observations did not support the role of primary exenteration. Five patients (11%) with extrascleral extension had orbital recurrences and all died within 31 months of surgery regardless of treatment.

摘要

在一项回顾性研究中，610例睫状体或脉络膜恶性黑色素瘤患者中有50例（8.2%）出现巩膜外扩展。在有随访数据的46例患者中，24例（52%）存活了5年，20例（42%）存活了10年，17例（37%）存活了15年。似乎对生存有显著影响的因素包括眼内肿瘤大小、眼外肿瘤大小和位置。我们的观察结果不支持原发灶眼球摘除术的作用。5例（11%）有巩膜外扩展的患者出现眼眶复发，无论接受何种治疗，均在手术后31个月内死亡。