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为期一个月的全食物植物性营养教育计划可降低低密度脂蛋白、糖化血红蛋白并减少炎症标志物。

One Month Whole Food Plant-Based Nutrition Educational Program Lowers LDL, A1C, and Decreases Inflammatory Markers.

作者信息

Musial Sandra, Burns Zachary, Bertman Jack, Fitzgibbon Molly, Mashek Rachel, Risica Patricia Markham

机构信息

Plant Docs, Providence, RI, USA.

Department of Family Medicine, Brown University Warren Alpert Medical School, Providence, RI, USA.

出版信息

Am J Lifestyle Med. 2024 Nov 1:15598276241291490. doi: 10.1177/15598276241291490.

DOI:10.1177/15598276241291490
PMID:39540160
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11556590/
Abstract

Lifestyle-related chronic disease increases in the United States have led to the need for innovative programs targeting dietary choices. Based on growing evidence supporting whole food plant-based (WFPB) nutrition to improve overall health, we devised a one-month WFPB intervention program, Jumpstart Your Health! (JYH), to introduce and encourage adoption of the WFPB dietary lifestyle. This paper investigates its effects on various health indicators associated with cardiovascular and metabolic diseases. Among the total of 150 participants, before and after physical measurements and blood chemistries demonstrate significant (p< 0.05) decreases in weight (-4.2 pounds), cholesterol (-25.3 mg/dl), LDL (-19.0 mg/dl), HDL (-5.6 mg/dl), hemoglobin A1c (-0.2%), and hsCRP (-1.9 mg/L). Among the high-risk participants, we found significant decreases in systolic blood pressure (-10 mmHg), diastolic blood pressure (-8.7 mmHg), weight (-4.3 pounds), cholesterol (-38.8 mg/dl), LDL (-22.7 mg/dl), HDL (-2.8 mg/dl), hemoglobin A1c (-0.2 %), and hsCRP (-2.3 mg/L). We demonstrate that a simple WFPB intervention implemented over one month resulted in significant reductions in physical measurements and blood chemistries that could translate to lowered risk or improvement for obesity, cardiovascular disease, and type-2 diabetes.

摘要

美国与生活方式相关的慢性病增多,这就需要针对饮食选择制定创新项目。基于越来越多的证据支持以全食物植物性(WFPB)营养来改善整体健康状况,我们设计了一个为期一个月的WFPB干预项目“启动你的健康!”(JYH),以介绍并鼓励人们采用WFPB饮食生活方式。本文调查了该项目对与心血管和代谢疾病相关的各项健康指标的影响。在总共150名参与者中,身体测量和血液化学指标在干预前后显示出体重(-4.2磅)、胆固醇(-25.3毫克/分升)、低密度脂蛋白(-19.0毫克/分升)、高密度脂蛋白(-5.6毫克/分升)、糖化血红蛋白(-0.2%)和超敏C反应蛋白(-1.9毫克/升)均显著下降(p<0.05)。在高危参与者中,我们发现收缩压(-10毫米汞柱)、舒张压(-8.7毫米汞柱)、体重(-4.3磅)、胆固醇(-38.8毫克/分升)、低密度脂蛋白(-22.7毫克/分升)、高密度脂蛋白(-2.8毫克/分升)、糖化血红蛋白(-0.2%)和超敏C反应蛋白(-2.3毫克/升)均有显著下降。我们证明,实施为期一个月的简单WFPB干预可显著降低身体测量和血液化学指标,这可能转化为降低肥胖、心血管疾病和2型糖尿病的风险或改善病情。

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