Grassi Giacomo, Moradei Corinna, Cecchelli Chiara, van Ameringen Michael
Brain Center Firenze, Florence, Italy.
Department of Psychiatry and Behavioural Neurosciences, MacAnxiety Research Centre, McMaster University, Hamilton, Canada.
Int J Psychiatry Clin Pract. 2024 Jun;28(2):167-176. doi: 10.1080/13651501.2024.2427615. Epub 2024 Nov 15.
Several studies consistently showed that patients with attention deficit hyperactivity disorder (ADHD) have high rates of hoarding disorder (HD) comorbidity. The aim of the present study was to compare the clinical and cognitive features of adult ADHD patients with and without hoarding comorbidity according to a self-report measure, and a sample of healthy controls.
Fifty-seven consecutive adult outpatients with a primary diagnosis of ADHD with comorbid hoarding disorder (ADHD+HD), 57 matched ADHD patients without hoarding disorder comorbidity (ADHD-HD), and a control group of 47 healthy controls (HCs) were enrolled. All subjects undergone a comprehensive clinical assessment and a neurocognitive assessment focused on attention, memory, and executive functions.
The ADHD groups differed on most of the clinical and cognitive measures compared to HCs. ADHD+HD patients showed similar ADHD symptoms but greater subjective impulsivity, mood and anxiety symptoms, and a greater functional impairment compared to ADHD-HD patients as well as greater attentional and executive functioning impairments.
ADHD patients with comorbid hoarding disorder present a more complex clinical and neuropsychological phenotype correlated to a greater functional impairment compared to ADHD patients without this comorbidity. These results further highlight the relevance of assessing and treating hoarding behaviours in adults with ADHD.
多项研究一致表明，注意缺陷多动障碍（ADHD）患者的囤积障碍（HD）合并症发生率很高。本研究的目的是根据一项自我报告测量方法，对有和没有囤积合并症的成年ADHD患者以及一组健康对照者的临床和认知特征进行比较。
纳入了57例连续的成年门诊患者，他们的主要诊断为ADHD合并囤积障碍（ADHD+HD），57例匹配的无囤积障碍合并症的ADHD患者（ADHD-HD），以及一个由47名健康对照者（HCs）组成的对照组。所有受试者均接受了全面的临床评估和侧重于注意力、记忆和执行功能的神经认知评估。
与健康对照者相比，ADHD组在大多数临床和认知测量指标上存在差异。与ADHD-HD患者相比，ADHD+HD患者表现出相似的ADHD症状，但主观冲动性、情绪和焦虑症状更严重，功能损害更大，注意力和执行功能损害也更大。
与无此合并症的ADHD患者相比，合并囤积障碍的ADHD患者表现出更复杂的临床和神经心理学表型，且与更大的功能损害相关。这些结果进一步凸显了评估和治疗成年ADHD患者囤积行为的重要性。
