OBJECTIVE: We reviewed our institutional experience of radical prostatectomy with and without preoperative multiparametric magnetic resonance imaging (mpMRI) to assess the impact of preoperative prostate mpMRI on surgical outcomes of radical prostatectomy. METHODS: We identified patients at our institution who underwent radical prostatectomy for prostate cancer (PCa) between January 2012 and December 2017 ( = 1044). Using propensity scoring analysis, patients who underwent preoperative mpMRI ( = 285) were matched 1:1 to patients who did not receive preoperative mpMRI ( = 285). Multivariable regression analysis was performed to identify factors predictive of operative time, estimated blood loss (EBL), lymph node yield, rates of complications within 30 days, and positive surgical margin (PSM). RESULTS: There were no significant differences in operative time, EBL, PSM, lymph node yield, or complication rates between the two cohorts. Multivariable analysis demonstrated that preoperative mpMRI was not predictive of the measured perioperative outcomes. Significant comorbidity (Charlson Comorbidity Index ≥3) was the sole predictor of perioperative complications ( = 0.015). Increasing biopsy Gleason score predicted increased lymph node yield ( < 0.001). The probability of PSM was associated with increasing preoperative prostate-specific antigen (odds ratio 1.036, = 0.009). Body mass index was a predictor of operative time ( = 0.016) and EBL ( = 0.001). CONCLUSIONS: Although preoperative mpMRI has an important role in the diagnosis and staging of PCa, it does not impact perioperative radical prostatectomy outcomes. Our findings do not support the routine use of preoperative mpMRI for surgical planning in patients already diagnosed with clinically localized PCa.