Department of Family Medicine, Taichung Veterans General Hospital, Taichung, Taiwan.
Institute of Medicine, Chung Shan Medical University, Taichung, Taiwan.
Sci Rep. 2024 Nov 18;14(1):28460. doi: 10.1038/s41598-024-79888-w.
Bone health screening is crucial before and during androgen deprivation therapy (ADT) for prostate cancer, yet changes in bone mineral density during ADT are often overlooked. To improve surveillance rates, we developed an auto-recruit path integrated into the outpatient system, where a pop-up reminder prompts physicians to arrange bone health screenings when ADT is prescribed without a dual-energy x-ray absorptiometry (DXA) screening in the past year. If selected, the system orders DXA and related examinations automatically. We retrospectively reviewed DXA screening rates from 2000 to 2018. During that period, only 286 out of 3,019 patients (9.5%) received DXA screenings. After implementing the auto-recruit system, 251 out of 747 eligible patients (33.6%) were screened from March 2021 to February 2022. Participants using ADT for over a year had worse T-scores and higher osteoporosis rates (34.5% vs. 23.2%) compared to those using ADT for less than a year. Post-screening, there was a significant increase in calcium supplement and bone protective agent use, highlighting improved patient awareness and proactive bone health management. In conclusion, bone health screening for prostate cancer patients on ADT remains an unmet need. The auto-recruit path in the outpatient system effectively increases screening rates and enhances bone health management.
骨健康筛查在前列腺癌患者接受雄激素剥夺治疗(ADT)之前和期间至关重要,但 ADT 期间的骨密度变化往往被忽视。为了提高监测率,我们开发了一种自动招募路径,集成到门诊系统中,当 ADT 被开处方而过去一年没有进行双能 X 线吸收法(DXA)筛查时,弹出提醒会提示医生安排骨健康筛查。如果选择,系统会自动订购 DXA 和相关检查。我们回顾性地审查了 2000 年至 2018 年的 DXA 筛查率。在此期间,只有 3019 名患者中的 286 名(9.5%)接受了 DXA 筛查。在实施自动招募系统后,2021 年 3 月至 2022 年 2 月,747 名符合条件的患者中有 251 名(33.6%)接受了筛查。与使用 ADT 不到一年的患者相比,使用 ADT 超过一年的患者的 T 评分更差,骨质疏松症发生率更高(34.5%比 23.2%)。筛查后,钙补充剂和骨保护剂的使用显著增加,这突出了患者意识的提高和积极的骨健康管理。总之,前列腺癌患者接受 ADT 后的骨健康筛查仍然是一个未满足的需求。门诊系统中的自动招募路径有效地提高了筛查率,并增强了骨健康管理。