Shahabinejad Erfan, Shakoeizadeh Amirreza, Vakilian Alireza, Alipour Seyyed Mohammad, Jalali Fatemeh, Ebrahimi Faezeh, Mashyekhi Narges
Student Research Committee, Faculty of Medicine, Rafsanjan University of Medical Sciences, Rafsanjan, Iran.
USERN Office, Rafsanjan University of Medical Sciences, Rafsanjan, Iran.
J Neurovirol. 2024 Dec;30(5-6):559-564. doi: 10.1007/s13365-024-01237-4. Epub 2024 Nov 19.
Guillain-Barre Syndrome (GBS) is a rare but serious neurological disorder characterized by acute flaccid paralysis and areflexia, usually after an infectious disease. This case report describes a previously healthy 9-year-old boy who developed GBS following an acute hepatitis A infection. The patient presented with rapidly progressive weakness, ascending paralysis, and areflexia, confirmed by clinical and electrophysiological findings. Results were consistent with the GBS subgroup of Acute Motor Axonal Neuropathy. Treatment with intravenous immunoglobulin (IVIG) led to gradual improvement, highlighting the importance of early recognition and intervention. This report reviews the current literature on the association between GBS and hepatitis A, emphasizing the rarity of such cases in pediatric populations. The report aims to raise awareness among clinicians about this potential complication of hepatitis A, underscoring the need for prompt diagnosis and treatment to improve outcomes in similar cases. The report emphasizes the need for prompt diagnosis and treatment to improve outcomes in similar cases.
吉兰-巴雷综合征（GBS）是一种罕见但严重的神经系统疾病，通常在感染性疾病后出现，其特征为急性弛缓性麻痹和腱反射消失。本病例报告描述了一名此前健康的9岁男孩，在急性甲型肝炎感染后患上了GBS。患者表现为迅速进展的肌无力、上行性麻痹和腱反射消失，临床和电生理检查结果证实了这一点。结果与急性运动轴索性神经病这一GBS亚组相符。静脉注射免疫球蛋白（IVIG）治疗导致病情逐渐改善，突出了早期识别和干预的重要性。本报告回顾了关于GBS与甲型肝炎之间关联的当前文献，强调了此类病例在儿科人群中的罕见性。该报告旨在提高临床医生对甲型肝炎这种潜在并发症的认识，强调在类似病例中需要及时诊断和治疗以改善预后。该报告强调在类似病例中需要及时诊断和治疗以改善预后。
