Waxman M, Vuletin J C, Rosenblatt P, Herzberg F P
Histopathology. 1986 Feb;10(2):207-15. doi: 10.1111/j.1365-2559.1986.tb02475.x.
An adenocarcinoma which arose in a dermoid cyst of the ovary displayed areas of melanocyte colonization and pigmentation. Ultrastructural study revealed the presence of epithelial tumour cells and melanocytes; many tumour cells contained compound melanosomes, but not premelanosomes, suggesting transfer of melanin from melanocytes to tumour cells. Melanocyte colonization of malignant tumours is a curious phenomenon the significance of which remains to be elucidated.
起源于卵巢皮样囊肿的腺癌呈现出黑素细胞定植和色素沉着区域。超微结构研究显示存在上皮肿瘤细胞和黑素细胞;许多肿瘤细胞含有复合黑素小体,但不含前黑素小体,提示黑色素从黑素细胞转移至肿瘤细胞。恶性肿瘤中的黑素细胞定植是一种奇特的现象,其意义尚待阐明。