Ruggeri Matteo, Signorini Alessandro, Caravaggio Silvia, Righi Gabriele
Istituto Nazionale di Statistica (ISTAT), Rome - Italy.
Health Economics Evaluation (HEE) Research Unit, UniCamillus Medical University, Rome - Italy.
Glob Reg Health Technol Assess. 2024 Nov 18;11:214-222. doi: 10.33393/grhta.2024.3168. eCollection 2024 Jan-Dec.
The objective of this study is to evaluate the economic impact of the device Navina Smart on patients affected by neurogenic bowel dysfunction and dependent on transanal irrigation within the Italian context. This study employs the perspective of the Italian National Health Service.
The analysis was conducted through a Markov model, comparing two scenarios: standard bowel care vs. transanal irrigation. The model operates on a 30-year time period. The results were reported in terms of net monetary benefit.
Transanal irrigation therapy was dominant in all scenarios with lower costs and higher effectiveness. The population was assumed to be composed of 1,000 subjects. Setting the willingness to pay at €35,000.00/QALYs (quality-adjusted life years), the analysis yielded a net monetary benefit of €81,087 and cost savings of €66,101 per patient over 30 years.
The results of this study substantiate that transanal irrigation therapy treatment employing the Navina Smart device can significantly benefit patients suffering from neurogenic bowel dysfunction by relieving their symptoms. In addition, this therapy offers important cost savings for the Italian National Health Service by reducing resource utilization.
本研究的目的是在意大利背景下，评估Navina Smart设备对受神经源性肠道功能障碍影响且依赖经肛门灌洗的患者的经济影响。本研究采用意大利国家医疗服务体系的视角。
通过马尔可夫模型进行分析，比较两种方案：标准肠道护理与经肛门灌洗。该模型在30年的时间范围内运行。结果以净货币效益报告。
在所有方案中，经肛门灌洗疗法均占主导地位，成本更低且效果更佳。假设研究人群由1000名受试者组成。将支付意愿设定为35,000.00欧元/质量调整生命年（QALYs），分析得出在30年期间每位患者的净货币效益为81,087欧元，成本节约为66,101欧元。
本研究结果证实，采用Navina Smart设备的经肛门灌洗疗法可通过缓解症状，使患有神经源性肠道功能障碍的患者显著受益。此外，该疗法通过减少资源利用，为意大利国家医疗服务体系节省了大量成本。
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