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巴基斯坦高身体质量指数(BMI)妊娠与产妇发病率和死亡率的关系。

RELATIONSHIP OF MATERNAL MORBIDITY AND MORTALITY TO HIGH BODY MASS INDEX (BMI) PREGNANCIES IN PAKISTAN.

机构信息

Dow University of Health Sciences, DRKMP Civil Hospital, Karachi-Pakistan.

出版信息

J Ayub Med Coll Abbottabad. 2024 Jan-Mar;36(1):93-97. doi: 10.55519/JAMC-01-12645.

Abstract

BACKGROUND

The average BMI is shifting upwards even in low-resource countries like Pakistan causing an increase in pregnancy-related complications. This study was planned to elaborate the association of maternal morbidity and mortality during pregnancy and puerperium with high BMI.

METHODS

A descriptive longitudinal study was performed in the Obstetrics and Gynaecology Unit 2 of D. Ruth K. M. Pfau Civil Hospital, Karachi, Pakistan from 1st August 2022 to 31st January 2023. Women delivering in Obstetric Unit 2 having a 1st-trimester record of weight were included. Demographic data, antenatal, intrapartum and postpartum complications noted. Participants were further stratified into 2 groups based on BMI, i.e., overweight (25.0-29.9) and obese (30.0 or more) and demographics and clinical characteristics compared. Univariate and multivariate logistic regression analysis was done. Data was entered and analyzed on SPSS version 21.

RESULTS

The frequency is calculated to be 15.7%. The observed complications included pre-eclampsia 16.7%, PIH 13%, eclampsia 7%, GDM 18.9%, induction of labour 19.5%, PPH in 15.2% and infected caesarean wound in 19.2% of participants. The caesarean section was the predominant mode of delivery in 55.7%. A significant relationship was found with advancing maternal age, DM/ GDM, hypertension, Pre-eclampsia, IOL, caesarean section, PPH and wound infection. The univariate and multivariate logistic regression models also showed two times higher odd in obese groups as compared to overweight groups.

CONCLUSIONS

Our study underscores a strong association between maternal obesity in early pregnancy and several threatening complications during pregnancy, delivery, and the postpartum period.

摘要

背景

即使在巴基斯坦等资源匮乏的国家,平均 BMI 值也在上升,导致与妊娠相关的并发症增加。本研究旨在详细阐述孕产妇在妊娠和产褥期的发病率和死亡率与高 BMI 值之间的关系。

方法

本研究为 2022 年 8 月 1 日至 2023 年 1 月 31 日在巴基斯坦卡拉奇 D. Ruth K. M. Pfau 公民医院妇产科 2 区进行的描述性纵向研究。纳入在产科 2 区分娩且在妊娠早期有体重记录的妇女。记录人口统计学数据、产前、产时和产后并发症。根据 BMI 将参与者进一步分为两组,即超重(25.0-29.9)和肥胖(30.0 或更高),并比较两组的人口统计学和临床特征。进行单变量和多变量逻辑回归分析。数据输入和分析使用 SPSS 版本 21 进行。

结果

计算得出的频率为 15.7%。观察到的并发症包括先兆子痫 16.7%、妊娠高血压 13%、子痫 7%、妊娠期糖尿病 18.9%、引产 19.5%、产后出血 15.2%和感染性剖宫产伤口 19.2%。剖宫产是 55.7%的主要分娩方式。随着产妇年龄、DM/GDM、高血压、先兆子痫、IOL、剖宫产、PPH 和伤口感染的增加,发现两者之间存在显著关系。单变量和多变量逻辑回归模型还显示,肥胖组的几率是超重组的两倍。

结论

我们的研究强调了早孕时母亲肥胖与妊娠、分娩和产褥期期间的多种威胁性并发症之间的密切关系。

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