SURGICAL OUTCOMES OF TRACTIONAL MACULOPATHY ASSOCIATED WITH FAMILIAL EXUDATIVE VITREORETINOPATHY IN CHILDREN.

PURPOSE

To evaluate the surgical outcomes of pediatric familial exudative vitreoretinopathy complicated by tractional maculopathy.

METHODS

Retrospective case series. Chart review of 14 children (15 eyes) diagnosed with tractional maculopathy-complicated familial exudative vitreoretinopathy who received vitrectomy.

RESULTS

The mean age at surgery was 7.2 years. The mean follow-up duration was 14.1 months. The logarithm of the minimum angle of resolution of best-corrected visual acuity improved from 1.0 ± 0.6 (20/200 Snellen) to 0.6 ± 0.6 (20/80 Snellen) postoperation (t = 4.293, P = 0.001). The peripapillary temporal inner angle [63.9 (15.7)° vs. 71.1 (31.2)°, z = -2.726, P = 0.006] and peripapillary temporal outer angle (63.4 ± 25.2° vs. 69.6 ± 23.5°, t = -2.820, P = 0.014) widened postoperation. Postoperative best-corrected visual acuity was superior in eyes with a shorter time between symptom onset and surgery (r = 0.688, P = 0.019), better preoperative logarithm of the minimum angle of resolution best-corrected visual acuity (r = 0.830, P < 0.001), and preoperative widening of the outer nuclear layer (r-pb = 0.730, P = 0.007) and foveal avascular zone (r-pb = 0.794, P = 0.002), and in eyes with postoperative ellipsoid (r-pb = 0.641, P = 0.018) and interdigitation zones integrity (r-pb = 0.614, P = 0.026), widening of the outer nuclear layer (r-pb = 0.816, P = 0.001) and foveal avascular zone (r-pb = 0.940, P < 0.001), and absence of the inner retinal layer at the fovea (r-pb = 0.672, P = 0.012).

CONCLUSION

Vitrectomy is effective for pediatric familial exudative vitreoretinopathy complicated by tractional maculopathy. Patient selection is crucial and iatrogenic complications should be avoided.