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克服人类医学与兽医学跨学科合作中的挑战。

Overcoming Challenges in Interdisciplinary Collaboration Between Human and Veterinary Medicine.

作者信息

Han Louise, Lee Yerhee, Lee Hyunsu, Lee Hyejin, Lee Jeong-Ik

机构信息

Regenerative Medicine Laboratory, Center for Stem Cell Research, Department of Biomedical Science and Technology, Institute of Biomedical Science and Technology, Konkuk University, Seoul 05029, Republic of Korea.

Chadwick International School, 45 Art Center-Daero 97 Beon-Gil, Yeonsu-gu, Incheon 22002, Republic of Korea.

出版信息

Vet Sci. 2024 Oct 23;11(11):518. doi: 10.3390/vetsci11110518.

Abstract

Companion animals, such as dogs and cats, have gained considerable attention in translational medicine due to their potential as models for human diseases. The use of these animals in research has opened new avenues for developing treatments that can benefit both human and veterinary patients, aligning with the One Health approach. Unlike traditional laboratory models like mice, rats, and rabbits, companion animals naturally develop diseases that closely mirror those in humans, including but not limited to diabetes, aging, cancer, and neurological disorders, making them particularly valuable in translational research. Recent advances have highlighted the role of companion animals in enhancing the effectiveness of novel therapies during clinical trials, as they are exposed to diverse environmental and lifestyle factors similar to those experienced by humans. However, the integration of companion animals into translational medicine presents challenges, particularly in terms of collaboration between veterinary and human medicine, where terminology differences in anatomy, clinical terminology, and animal classification can lead to miscommunication. In conclusion, these findings underscore the need for better implementation of the One Health approach by uniting the fragmented collaboration between veterinarians and doctors through interdisciplinary training and fostering unified efforts across both fields, with experts from various disciplines contributing their specialized knowledge in clinical practice and research.

摘要

伴侣动物,如狗和猫,因其作为人类疾病模型的潜力而在转化医学中受到了相当大的关注。在研究中使用这些动物为开发能使人类和兽医患者都受益的治疗方法开辟了新途径,这与“同一健康”理念相一致。与小鼠、大鼠和兔子等传统实验室模型不同,伴侣动物自然会患上与人类疾病极为相似的疾病,包括但不限于糖尿病、衰老、癌症和神经疾病,这使得它们在转化研究中具有特别重要的价值。最近的进展凸显了伴侣动物在提高临床试验中新型疗法有效性方面的作用,因为它们接触到与人类相似的各种环境和生活方式因素。然而,将伴侣动物纳入转化医学也带来了挑战,特别是在兽医医学和人类医学之间的合作方面,解剖学、临床术语和动物分类方面的术语差异可能导致沟通不畅。总之,这些发现强调了通过跨学科培训将兽医和医生之间分散的合作联合起来,并促进两个领域的统一努力,让各学科专家在临床实践和研究中贡献其专业知识,从而更好地实施“同一健康”理念的必要性。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/cf20/11598837/46c8ddf0d405/vetsci-11-00518-g001.jpg

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