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[不可手术切除肺癌患者的放射治疗效果]

[Effectiveness of radiotherapy of patients with inoperable lung cancer].

作者信息

Muravskaia G V, Artemova N A

出版信息

Med Radiol (Mosk). 1986 Apr;31(4):39-43.

PMID:3959811
Abstract

Data on 203 patients with locally advanced lung cancer subjected to exploratory thoracotomy were studied: the 1st group--68 patients received symptomatic therapy only, the 2nd group--71 patients received a palliative course of radiotherapy, and the 3rd group--64 patients were on radiotherapy after a radical program. Radiotherapy in the 3rd group was performed after a split course using staged change of dose fractionation regimens. The use of the palliative radiotherapy course brought about a subjective effect in 39.0 5% of the patients but had no effect upon their survival. Radiotherapy after a radical program resulted in a subjective effect in 82.8 +/- 5.2% of patients and objective improvement in 56.3 6%. The mean survival time of the patients in the 3rd group was twice as much as compared to the patients in the 1st group, being 13.8 mos. versus 6 mos. In the 3rd group 15.4 +/- 7.2% of the patients lived over 3 yrs. Whereas none of the patients in the 1st and 2nd groups had survived by that time. Better results were obtained in the group of patients with epidermoid lung cancer.

摘要

对203例接受 exploratory thoracotomy 的局部晚期肺癌患者的数据进行了研究:第一组——68例患者仅接受对症治疗;第二组——71例患者接受了姑息性放疗疗程;第三组——64例患者在接受根治性方案后进行放疗。第三组的放疗在采用分阶段改变剂量分割方案的分段疗程后进行。姑息性放疗疗程使39.05%的患者产生了主观效果,但对其生存率没有影响。根治性方案后放疗使82.8±5.2%的患者产生了主观效果,56.36%的患者有客观改善。第三组患者的平均生存时间是第一组患者的两倍,分别为13.8个月和6个月。第三组中15.4±7.2%的患者存活超过3年,而第一组和第二组中那时没有患者存活。在肺鳞状细胞癌患者组中获得了更好的结果。

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