Zeng Qiankun, Tang Ning, Shi Guoyue, Zhang Min
School of Chemistry and Molecular Engineering, In Situ Devices Research Center, Shanghai Key Laboratory for Urban Ecological Processes and Eco-Restoration, East China Normal University, Shanghai 200241, China.
Precision Research Center for Refractory Diseases in Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai 200025, China.
ACS Sens. 2024 Dec 27;9(12):6685-6697. doi: 10.1021/acssensors.4c02297. Epub 2024 Nov 27.
Biogels prepared from natural biopolymers are ideal candidates for constructing bioelectronics from the perspective of commercialization and environmental sustainability. However, discovering all-natural biogels that meet specific properties, such as mechanical properties, optical transparency, and stability, remains challenging. Here, our study introduces a revolutionary biogel library, a novel resource that significantly accelerates the discovery and application of suitable all-natural biogel materials for bioelectronics. Utilizing a high-throughput screening system designed with a frontend/backend development strategy, this biogel library facilitates the swift screening and customization of biogels, tailored to meet specific performance criteria. Along with demonstrating applications in soft bioelectronics and printed bioelectronics, this research also thoroughly investigates the recyclability and environmental impacts of biogels, setting a foundation for their use in sustainable, closed-loop ecological systems. This pioneering approach serves not only to foster the departure from petrochemical-derived polymers but also to bolster the advancement of environmentally responsible bioelectronics.
从商业化和环境可持续性的角度来看，由天然生物聚合物制备的生物凝胶是构建生物电子学的理想候选材料。然而，发现具有特定性能（如机械性能、光学透明度和稳定性）的全天然生物凝胶仍然具有挑战性。在这里，我们的研究引入了一个革命性的生物凝胶库，这是一种新型资源，可显著加速用于生物电子学的合适全天然生物凝胶材料的发现和应用。利用采用前端/后端开发策略设计的高通量筛选系统，这个生物凝胶库有助于快速筛选和定制生物凝胶，以满足特定的性能标准。除了展示在软生物电子学和印刷生物电子学中的应用外，这项研究还深入研究了生物凝胶的可回收性和环境影响，为其在可持续的闭环生态系统中的使用奠定了基础。这种开创性的方法不仅有助于推动摆脱石化衍生聚合物，还能促进对环境负责的生物电子学的发展。
