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应用头颅超声早期检测极低出生体重儿脑静脉窦血栓形成:病例报告及文献复习。

Early detection of cerebral sinus venous thrombosis in an extremely low birth weight infant using cranial ultrasound-case report and literature review.

机构信息

Clinical Department of Neonatology and Neonatal Intensive Care Unit, Saint Jadwiga the Queen Clinical Provincial Hospital No. 2, University of Rzeszów, 35-301, Rzeszów, Poland.

Department of Neonatology, Poznan University of Medical Sciences, 33 Polna Street, 60-535, Poznan, Poland.

出版信息

Childs Nerv Syst. 2024 Nov 27;41(1):7. doi: 10.1007/s00381-024-06659-3.

Abstract

INTRODUCTION

Cerebral sinus venous thrombosis (CSVT) is a serious condition in premature infants. Early diagnosis is crucial, as untreated CSVT can progress to severe complications such as delayed-onset intraventricular hemorrhage (IVH), which could lead to poor outcomes in this population.

RESEARCH QUESTION

This case highlights that serial cranial ultrasound can detect CSVT early, enabling prompt treatment and preventing subsequent complications.

METHODS AND MATERIALS

We present the case of an extremely low birth weight infant diagnosed with CSVT based on cranial ultrasonography findings. The patient had no clinical symptoms or previously detected brain injury.

RESULTS

Anticoagulant therapy was initiated immediately after diagnosis. Clot resolution was observed on cranial ultrasound after 5 days and confirmed by magnetic resonance imaging (MRI) on the 82 day of life (36 + 4 weeks of gestational age).

CONCLUSION

This case shows the significant value of cranial ultrasound as a diagnostic tool in premature infants when MRI is not immediately available. Early detection and treatment using ultrasound may help prevent severe complications.

摘要

介绍

脑窦静脉血栓形成(CSVT)是早产儿的一种严重病症。早期诊断至关重要,因为未经治疗的 CSVT 可进展为严重并发症,如迟发性脑室内出血(IVH),这可能导致该人群的不良结局。

研究问题

本病例强调了连续头颅超声检查可早期发现 CSVT,从而能够及时进行治疗并预防后续并发症。

方法和材料

我们报告了一例极低出生体重儿的病例,该患儿根据头颅超声检查结果诊断为 CSVT。患儿无临床症状或先前发现的脑损伤。

结果

诊断后立即开始抗凝治疗。头颅超声检查 5 天后观察到血栓溶解,并在第 82 天(36+4 周胎龄)的磁共振成像(MRI)上得到证实。

结论

本病例表明,在 MRI 无法立即获得的情况下,头颅超声作为一种诊断工具对早产儿具有重要价值。使用超声进行早期检测和治疗可能有助于预防严重并发症。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/869b/11602796/0a8f7d8a7ac7/381_2024_6659_Fig1_HTML.jpg

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