中国北方地区奶牛胃肠道线虫感染评估及相关风险因素分析。

Assessment of gastrointestinal nematode infections in dairy cattle and the associated risk factors in Northern China.

机构信息

School of Veterinary Medicine, Mongolian University of Life Sciences, Ulaanbaatar 17024, Mongolia.

Inner Mongolia Academy of Agricultural & Animal Husbandry Sciences, Inner Mongolia 010031, China.

出版信息

J Vet Sci. 2024 Nov;25(6):e73. doi: 10.4142/jvs.24173.

DOI:10.4142/jvs.24173

PMID:39608768

原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11611495/

Abstract

IMPORTANCE

Gastrointestinal nematodiasis poses significant economic losses in the livestock industry due to mortality, morbidity, and decreased production.

OBJECTIVE

This study examined the prevalence of gastrointestinal nematodiasis in dairy cattle in Central Inner Mongolia, Northern China, the associated risk factors, and the effects on the pepsinogen and gastrin levels.

METHODS

Fecal samples (n = 590) were collected from four regions and analyzed using the standard floatation and sedimentation techniques. The serum gastrin and pepsinogen levels were also assessed as potential biomarkers for gastrointestinal nematodiasis.

RESULTS

Among 590 animals, 259 (43.9%; 95% confidence interval, 36.7-49.8) tested positive for at least one type of gastrointestinal nematode parasite. Among the positive animals, 38.6% were poly-parasitic, while 61.4% were mono-parasitic ( < 0.05). was the predominant nematode among mono-infections, accounting for 10.8%, followed in order by (10.0%), (9.6%), (8.5%), (6.9%), (6.9%), (4.6%), and (3.9%). Among the poly-parasitic infected cattle, 22.7%, 9.3%, 4.2%, and 2.3% had two, three, four, and five parasite combinations, respectively. The risk factors, such as age, breed, area, physical condition, and presence of diarrhea, were significantly ( < 0.05) associated with the prevalence of gastrointestinal nematodiasis. Poly-parasitic infected cattle showed 49.1% higher ( = 0.013) serum pepsinogen levels than the control group, while the mono-parasitic ones exhibited a 28.33% increase ( = 0.030). Similarly, the serum gastrin levels increased by 99.2% ( = 0.004) and 71.3% ( = 0.015) in the poly-parasitic and mono-parasitic animals, respectively.

CONCLUSIONS AND RELEVANCE

These findings demonstrate the high prevalence of gastrointestinal nematodiasis in Northern China, with an alarming rate of poly-parasitic infections. In addition, polyparasitic infections affect the enzymes pepsinogen and gastrin levels.

摘要

重要性

由于死亡率、发病率和生产力下降，胃肠道线虫病给畜牧业造成了巨大的经济损失。

目的

本研究调查了中国北方内蒙古中部地区奶牛胃肠道线虫病的流行情况、相关危险因素以及对胃蛋白酶原和胃泌素水平的影响。

方法

采集了来自四个地区的 590 份粪便样本，采用标准漂浮和沉淀技术进行分析。还评估了血清胃泌素和胃蛋白酶原水平作为胃肠道线虫病的潜在生物标志物。

结果

在 590 只动物中，有 259 只（43.9%；95%置信区间，36.7-49.8）至少检测到一种胃肠道线虫寄生虫呈阳性。在阳性动物中，38.6%为多寄生虫感染，而 61.4%为单寄生虫感染（<0.05）。在单感染中，是主要的线虫，占 10.8%，其次是（10.0%）、（9.6%）、（8.5%）、（6.9%）、（6.9%）、（4.6%）和（3.9%）。在多寄生虫感染的牛中，22.7%、9.3%、4.2%和 2.3%分别有两种、三种、四种和五种寄生虫组合。年龄、品种、地区、身体状况和腹泻存在等危险因素与胃肠道线虫病的流行显著相关（<0.05）。多寄生虫感染的牛血清胃蛋白酶原水平比对照组高 49.1%（=0.013），单寄生虫感染的牛血清胃蛋白酶原水平高 28.33%（=0.030）。同样，多寄生虫和单寄生虫感染的牛血清胃泌素水平分别增加了 99.2%（=0.004）和 71.3%（=0.015）。